New crystal forms of Diocleinae lectins in the presence of different dimannosides

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dc.contributor.authorMendes Batista Moreno, Frederico Bruno
dc.contributor.authorBezerra, Gustavo Arruda
dc.contributor.authorMaia de Oliveira, Taiana
dc.contributor.authorPrata de Souza, Emmanuel
dc.contributor.authorMatias da Rocha, Bruno Anderson
dc.contributor.authorBenevides, Raquel Guimaraes
dc.contributor.authorDelatorre, Plinio
dc.contributor.authorCavada, Benildo Sousa
dc.contributor.authorFilgueira de Azevedo, Walter
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Ceará (UFC)
dc.contributor.institutionUniv Reg Cariri
dc.contributor.institutionPontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
dc.date.accessioned2014-05-20T15:21:07Z
dc.date.available2014-05-20T15:21:07Z
dc.date.issued2006-11-01
dc.description.abstractStudying the interactions between lectins and sugars is important in order to explain the differences observed in the biological activities presented by the highly similar proteins of the Diocleinae subtribe. Here, the crystallization and preliminary X--ray data of Canavalia gladiata lectin (CGL) and C. maritima lectin (CML) complexed with Man(alpha 1-2)Man(alpha 1)OMe, Man(alpha 1-3)Man(alpha 1)OMe and Man(alpha 1-4)Man(alpha 1)OMe in two crystal forms [the complexes with Man(alpha 1-3)Man(alpha 1)OMe and Man(alpha 1-4)Man(alpha 1)OMe crystallized in space group P3(2) and those with Man(alpha 1-2)Man(alpha 1)OMe crystallized in space group I222], which differed from those of the native proteins (P2(1)2(1)2 for CML and C222 for CGL), are reported. The crystal complexes of ConA-like lectins with Man(alpha 1-4)Man(alpha 1)OMe are reported here for the first time.en
dc.description.affiliationUniv Estadual Paulista, IBILCE, Dept Fis, BR-15054000 Sao Jose do Rio Preto, Brazil
dc.description.affiliationUniv Fed Ceara, Dept Bioquim & Biol Mol, Biomol Lab, BR-60455970 Fortaleza, Ceara, Brazil
dc.description.affiliationUniv Reg Cariri, Dept Ciências Biol, BR-63195000 Crato, Ceara, Brazil
dc.description.affiliationPUCRS, Fac Biociencias, BR-90619900 Porto Alegre, RS, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, IBILCE, Dept Fis, BR-15054000 Sao Jose do Rio Preto, Brazil
dc.format.extent1100-1103
dc.identifierhttp://dx.doi.org/10.1107/S1744309106038887
dc.identifier.citationActa Crystallographica Section F-structural Biology and Crystallization Communications. Oxford: Blackwell Publishing, v. 62, p. 1100-1103, 2006.
dc.identifier.doi10.1107/S1744309106038887
dc.identifier.issn1744-3091
dc.identifier.urihttp://hdl.handle.net/11449/32299
dc.identifier.wosWOS:000241681700011
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.relation.ispartofActa Crystallographica Section F: Structural Biology and Crystallization Communications
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleNew crystal forms of Diocleinae lectins in the presence of different dimannosidesen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Publishing
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Pretopt

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