Use of bovine bone graft and bone membrane in defects surgically created in the cranial vault of rabbits. Histologic comparative analysis

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dc.contributor.authorQueiroz, T. P.
dc.contributor.authorHochuli-Vieira, D.
dc.contributor.authorGabrielli, MAC
dc.contributor.authorCancian, DCJ
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:46:55Z
dc.date.available2014-05-20T13:46:55Z
dc.date.issued2006-01-01
dc.description.abstractPurpose: This study was proposed to analyze histologically the process of repairing bone defects created surgically in the cranial vaults of rabbits. Materials and Methods: Thirty adult male rabbits (Oryctolagus cunilicus) received, under general anesthesia, bilateral parietal osteotomies by means of a 6mm-diameter trephine. The bony defects were divided into 4 groups. In group 1 the defect did not receive any treatment; in group 2 the defect was filled with lyophilized bovine bone (Biograft); in group 3 it was filled with bovine bone and covered with a bone matrix membrane (Bioplate); in group 4 it was covered with a bone matrix membrane. Animals were sacrificed in 3 equal groups at 15, 30, and 60 days. The specimens were subjected to routine laboratory procedures to evaluate the degree of bone repair. Results: After 60 days, new bone formation in group 2 was not satisfactory when compared to that of group 3. Large amounts of new bone formation in maturation were seen in group 3. In the defects covered with a membrane the results were similar to those of group 1 (ie, the cavity was filled with fibrous connective tissue). The implanted bone and membranes were totally resorbed. Discussion and Conclusions: the use of a membrane served as a barrier against the migration of cells from the adjacent tissue and the bone graft/membrane preserved the cavity space, resulting in an enhanced osteogenic effect.en
dc.description.affiliationUNESP, Dent Sch Araraquara, Div Oral & Maxillofacial Surg, Dept Diagnost & Surg, BR-14801930 São Paulo, Brazil
dc.description.affiliationUnespUNESP, Dent Sch Araraquara, Div Oral & Maxillofacial Surg, Dept Diagnost & Surg, BR-14801930 São Paulo, Brazil
dc.format.extent29-35
dc.identifierhttp://www.quintpub.com/journals/omi/abstract.php?article_id=2111#.UulUSLRTvIU
dc.identifier.citationInternational Journal of Oral & Maxillofacial Implants. Hanover Park: Quintessence Publishing Co Inc., v. 21, n. 1, p. 29-35, 2006.
dc.identifier.issn0882-2786
dc.identifier.urihttp://hdl.handle.net/11449/16648
dc.identifier.wosWOS:000235852100002
dc.language.isoeng
dc.publisherQuintessence Publishing Co Inc
dc.relation.ispartofInternational Journal of Oral & Maxillofacial Implants
dc.relation.ispartofjcr1.699
dc.relation.ispartofsjr1,576
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectbone graftingpt
dc.subjectbone regenerationpt
dc.subjectcranial vault reconstructionpt
dc.subjectresorbable membranespt
dc.subjectxenograftspt
dc.titleUse of bovine bone graft and bone membrane in defects surgically created in the cranial vault of rabbits. Histologic comparative analysisen
dc.typeArtigo
dcterms.licensehttp://www.quintpub.com/terms.php
dcterms.rightsHolderQuintessence Publishing Co Inc
unesp.author.orcid0000-0002-7147-1438[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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