Molecular modeling and small angle X-ray scattering studies of Hoplosternum littorale cathodic haemoglobin
dc.contributor.author | Peres, P. | |
dc.contributor.author | Lombardi, F. R. | |
dc.contributor.author | dos Santos, G. C. | |
dc.contributor.author | Olivieri, JR | |
dc.contributor.author | Canduri, F. | |
dc.contributor.author | Bonilla-Rodriguez, G. O. | |
dc.contributor.author | de Azevedo, W. F. | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Instituto Butantan | |
dc.date.accessioned | 2014-05-20T15:21:36Z | |
dc.date.available | 2014-05-20T15:21:36Z | |
dc.date.issued | 2004-12-10 | |
dc.description.abstract | Considerable interest is currently focused on fish haemoglobins in order to identify the structural basis for their diversity of functional behavior. Hoplosternum littorale is a catfish that presents bimodal gill (water)/gut (air) -breathing, which allows this species to survive in waters with low oxygen content. The hemolysate of this fish showed the presence of two main haemoglobins, cathodic and anodic. This work describes structural features analyzed here by integration of molecular modeling with small angle X-ray scattering. Here is described a molecular model for the cathodic haemoglobin in the unliganded and liganded states. The models were determined by molecular modeling based on the high-resolution crystal structure of fish haemoglobins. The structural models for both forms of H. littorale haemoglobin were compared to human haemoglobin. (C) 2004 Elsevier B.V. All rights reserved. | en |
dc.description.affiliation | UNESP, Dept Fis, Programa Pos Grad Biofis Mol, BR-15054000 Sao Jose Dos Campos, Brazil | |
dc.description.affiliation | Inst butantan, Ctr Appl Technol, BR-05503900 São Paulo, Brazil | |
dc.description.affiliation | UNESP, Dept Quim & Ciências Ambientais, BR-15054000 Sao Jose do Rio Preto, SP, Brazil | |
dc.description.affiliationUnesp | UNESP, Dept Fis, Programa Pos Grad Biofis Mol, BR-15054000 Sao Jose Dos Campos, Brazil | |
dc.description.affiliationUnesp | UNESP, Dept Quim & Ciências Ambientais, BR-15054000 Sao Jose do Rio Preto, SP, Brazil | |
dc.format.extent | 487-493 | |
dc.identifier | http://dx.doi.org/10.1016/j.bbrc.2004.10.061 | |
dc.identifier.citation | Biochemical and Biophysical Research Communications. San Diego: Academic Press Inc. Elsevier B.V., v. 325, n. 2, p. 487-493, 2004. | |
dc.identifier.doi | 10.1016/j.bbrc.2004.10.061 | |
dc.identifier.issn | 0006-291X | |
dc.identifier.lattes | 2406867656111498 | |
dc.identifier.uri | http://hdl.handle.net/11449/32722 | |
dc.identifier.wos | WOS:000225279600017 | |
dc.language.iso | eng | |
dc.publisher | Elsevier B.V. | |
dc.relation.ispartof | Biochemical and Biophysical Research Communications | |
dc.relation.ispartofjcr | 2.559 | |
dc.rights.accessRights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | catfish | pt |
dc.subject | cathodic haemoglobin | pt |
dc.subject | Hoplosternum littorale | pt |
dc.subject | molecular modeling | pt |
dc.subject | SAXS | pt |
dc.subject | bioinformatics | pt |
dc.subject | Structure | pt |
dc.title | Molecular modeling and small angle X-ray scattering studies of Hoplosternum littorale cathodic haemoglobin | en |
dc.type | Artigo | |
dcterms.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
dcterms.rightsHolder | Elsevier B.V. | |
unesp.author.lattes | 2406867656111498 | |
unesp.author.orcid | 0000-0001-9902-2557[6] | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Preto | pt |
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