Ultrastructural study of the lateral lobe of the prostate of Wistar rats submitted to experimental chronic alcohol ingestion

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dc.contributor.authorCagnon, V. H A
dc.contributor.authorGarcia, P. J. [UNESP]
dc.contributor.authorGuazzelli Filho, J. [UNESP]
dc.contributor.authorMartinez, F. E. [UNESP]
dc.contributor.authorMello, W. [UNESP]
dc.contributor.authorMartinez, M. [UNESP]
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:19:32Z
dc.date.available2014-05-27T11:19:32Z
dc.date.issued1998-01-01
dc.description.abstractAlcoholism is considered today one of the most serious social and medical problems. Different investigators have demonstrated that chronic exposure to alcohol causes morphological and physiological changes in the testes and in the accessory sex glands, in the prostate in particular. In the present study, experimental rats were divided into groups receiving sugar cane brandy diluted to 30° G.L. (30%, v/v) and Purina ration ad libitum for 60, 120, 180, 240 and 300 days, respectively. At the end of each period the animals were sacrificed and the lateral lobe of the prostate was collected for histological examination. The results showed atrophied epithelium, accumulation of lipidic droplets and rupture of the microvilli that line the cell surface facing the lumen of cells of the secretory epithelium of the lateral lobe of the prostate.en
dc.description.affiliationDepartment of Anatomy Institute of Biology State University of Campinas, São Paulo
dc.description.affiliationDepartment of Anatomy Institute of Biosciences São Paulo State University, Botucatu, São Paulo
dc.description.affiliationDepartment of Anatomy Institute of Biology State University of Campinas, 13083-970 Campinas, São Paulo
dc.description.affiliationUnespDepartment of Anatomy Institute of Biosciences São Paulo State University, Botucatu, São Paulo
dc.format.extent77-84
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/9530855
dc.identifier.citationJournal of Submicroscopic Cytology and Pathology, v. 30, n. 1, p. 77-84, 1998.
dc.identifier.issn1122-9497
dc.identifier.lattes6002949288271910
dc.identifier.lattes1739564105219382
dc.identifier.scopus2-s2.0-0031613626
dc.identifier.urihttp://hdl.handle.net/11449/65377
dc.language.isoeng
dc.relation.ispartofJournal of Submicroscopic Cytology and Pathology
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAlcohol
dc.subjectLateral lobe
dc.subjectUltrastructure
dc.subjectalcohol
dc.subjectalcoholism
dc.subjectanimal
dc.subjectdisease model
dc.subjectdrug effect
dc.subjectelectron microscopy
dc.subjectepithelium
dc.subjectlipid metabolism
dc.subjectmale
dc.subjectmale genital system
dc.subjectmetabolism
dc.subjectmicrovillus
dc.subjectpathology
dc.subjectprostate
dc.subjectrat
dc.subjecttime
dc.subjectultrastructure
dc.subjectWistar rat
dc.subjectAlcoholism
dc.subjectAnimals
dc.subjectDisease Models, Animal
dc.subjectEpithelium
dc.subjectEthanol
dc.subjectGenitalia, Male
dc.subjectLipid Metabolism
dc.subjectMale
dc.subjectMicroscopy, Electron
dc.subjectMicrovilli
dc.subjectProstate
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectTime Factors
dc.titleUltrastructural study of the lateral lobe of the prostate of Wistar rats submitted to experimental chronic alcohol ingestionen
dc.typeArtigo
unesp.author.lattes6002949288271910
unesp.author.lattes1739564105219382
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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