Metabolic syndrome and dementia associated with Parkinson's disease: Impact of age and hypertension

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dc.contributor.authorSchelp, Arthur Oscar [UNESP]
dc.contributor.authorMendes-Chiloff, Cristiane Lara [UNESP]
dc.contributor.authorBazan, Rodrigo [UNESP]
dc.contributor.authorPaduan, Vanessa Cristina [UNESP]
dc.contributor.authorPioltini, Ana Beatriz Maringolo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T02:43:30Z
dc.date.available2022-04-29T02:43:30Z
dc.date.issued2012-01-01
dc.description.abstractObjective: To determine correlations between age and metabolic disorders in Parkinson's disease (PD) patients. Methods: This observational cross-sectional study included brief tests for dementia and the Mattis test. Signals of metabolic syndrome were evaluated. Results: There was no significant effect from the presence of hypertension (OR=2.36 for patients under 65 years old and OR=0.64 for patients over 65), diabetes or hypercholesterolemia regarding occurrences of dementia associated with PD (24% of the patients). The study demonstrated that each year of age increased the estimated risk of dementia in PD patients by 9% (OR=1.09; 95%CI: 1.01-1.17). Conclusion: There was no evidence to correlate the presence of metabolic syndrome with the risk of dementia that was associated with PD. The study confirmed that dementia in PD is age dependent and not related to disease duration.en
dc.description.affiliationDepartment of Neurology Psychology and Psychiatry Botucatu Medical School São Paulo State University Júlio de Mesquita Filho (UNESP), Botucatu SP
dc.description.affiliationUnespDepartment of Neurology Psychology and Psychiatry Botucatu Medical School São Paulo State University Júlio de Mesquita Filho (UNESP), Botucatu SP
dc.format.extent114-118
dc.identifierhttp://dx.doi.org/10.1590/S0004-282X2012000200008
dc.identifier.citationArquivos de Neuro-Psiquiatria, v. 70, n. 2, p. 114-118, 2012.
dc.identifier.doi10.1590/S0004-282X2012000200008
dc.identifier.issn1678-4227
dc.identifier.issn0004-282X
dc.identifier.scopus2-s2.0-84856907497
dc.identifier.urihttp://hdl.handle.net/11449/226710
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofArquivos de Neuro-Psiquiatria
dc.sourceScopus
dc.subjectDementia
dc.subjectDyslipidemia
dc.subjectHypertension
dc.subjectParkinson's disease
dc.titleMetabolic syndrome and dementia associated with Parkinson's disease: Impact of age and hypertensionen
dc.titleSíndrome metabólica e demência associada à doença de parkinson: Impacto da idade e da hipertensão arterialpt
dc.typeArtigo

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