Lethal photosensitization and guided bone regeneration in treatment of peri-implantitis: an experimental study in dogs

dc.contributor.authorShibli, J. A.
dc.contributor.authorMartins, M. C.
dc.contributor.authorRibeiro, F. S.
dc.contributor.authorGarcia, V. G.
dc.contributor.authorNociti, F. H.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionGuarulhos Univ
dc.contributor.institutionUniversidade de Marília (UNIMAR)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.date.accessioned2014-02-26T17:24:53Z
dc.date.accessioned2014-05-20T13:45:09Z
dc.date.available2014-02-26T17:24:53Z
dc.date.available2014-05-20T13:45:09Z
dc.date.issued2006-06-01
dc.description.abstractThe purpose of this study was to evaluate the effect of lethal photosensitization and guided bone regeneration (GBR) on the treatment of ligature-induced peri-implantitis in different implant surfaces. The treatment outcome was evaluated by clinical and histometric methods. A total of 40 dental implants with four different surface coatings (10 commercially pure titanium surface (cpTi); 10 titanium plasma-sprayed (TPS); 10 acid-etched surface; 10 surface-oxide sandblasted) were inserted into five mongrel dogs. After 3 months, the animals with ligature-induced peri-implantitis were subjected to surgical treatment using a split-mouth design. The controls were treated by debridment and GBR, while the test side received an additional therapy with photosensitization, using a GaAlAs diode laser, with a wavelength of 830 nm and a power output of 50 mW for 80 s (4 J/cm(2)), and sensitized toluidine blue O (100 mu g/ml). The animals were sacrificed 5 months after therapy. The control sites presented an earlier exposition of the membranes on all coating surfaces, while the test group presented a higher bone height gain. Re-osseointegration ranged between 41.9% for the cpTi surface and 31.19% for the TPS surface in the test sites; however differences were not achieved between the surfaces. The lethal photosensitization associated with GBR allowed for better re-osseointegration at the area adjacent to the peri-implant defect regardless of the implant surface.en
dc.description.affiliationUNESP, Fac Odontol Araraquara, Dent Sch Araraquara, Dept Periodontol, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationGuarulhos Univ, Dept Periodontol, Dent Res Div, Guarulhos, SP, Brazil
dc.description.affiliationUniv Marilia, Dent Sch Marilia, Marilia, SP, Brazil
dc.description.affiliationUNESP, Dent Sch Aracatuba, Aracatuba, SP, Brazil
dc.description.affiliationUniv Estadual Campinas, Dent Sch Piracicaba, Dept Periodontol, Piracicaba, SP, Brazil
dc.description.affiliationUnespUNESP, Fac Odontol Araraquara, Dent Sch Araraquara, Dept Periodontol, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP, Dent Sch Aracatuba, Aracatuba, SP, Brazil
dc.format.extent273-281
dc.identifierhttp://dx.doi.org/10.1111/j.1600-0501.2005.01167.x
dc.identifier.citationClinical Oral Implants Research. Oxford: Blackwell Publishing, v. 17, n. 3, p. 273-281, 2006.
dc.identifier.doi10.1111/j.1600-0501.2005.01167.x
dc.identifier.issn0905-7161
dc.identifier.urihttp://hdl.handle.net/11449/15861
dc.identifier.wosWOS:000237259500006
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.relation.ispartofClinical Oral Implants Research
dc.relation.ispartofjcr4.305
dc.relation.ispartofsjr2,462
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectguided bone regenerationpt
dc.subjecthistologypt
dc.subjectperi-implantitispt
dc.subjectphotodynamic therapypt
dc.subjectphotosensitizerspt
dc.subjectre-osseointegrationpt
dc.titleLethal photosensitization and guided bone regeneration in treatment of peri-implantitis: an experimental study in dogsen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Publishing
unesp.author.orcid0000-0002-6715-8334[4]
unesp.author.orcid0000-0003-1971-0195[1]
unesp.author.orcid0000-0001-6809-8866[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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