Utilização do metabolismo protéico ( 15N-glicina) na detecção precoce de agravamento da atividade da doença em pacientes portadores de retocolite ulcerativa inespecífica

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dc.contributor.authorDichi, Isaias
dc.contributor.authorDichi, Jane B.
dc.contributor.authorFrenhane, Patrícia [UNESP]
dc.contributor.authorCorrêa, Camila Renata [UNESP]
dc.contributor.authorAngeleli, Aparecida Y.O. [UNESP]
dc.contributor.authorBicudo, Mitsue H. [UNESP]
dc.contributor.authorRodrigues, Maria A.M. [UNESP]
dc.contributor.authorVictória, Carlos R. [UNESP]
dc.contributor.authorBurini, Roberto Carlos [UNESP]
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:19:40Z
dc.date.available2014-05-27T11:19:40Z
dc.date.issued1998-12-01
dc.description.abstractDisease activity was assessed in 10 (five males and five females) ulcerative colitis patients through the following parameters: clinical, laboratory, sigmoidoscopic and histological. Protein metabolism was also assessed with 15N-glycine and urinary ammonia as end product. Only one patient had exacerbation of the disease two months after the study started. This patient presented in the beginning of the study protein synthesis and breakdown of 4.51 and 3.47 g protein/kg/day, respectively, values higher than all other patients, showing an hypermetabolic state, suggesting an increase of the disease activity. However, this increase was not detected by others indicators and indexes utilised. These data allow to suggest the hypothesis that protein metabolism predicts precociously the exacerbation of disease activity in ulcerative colitis patients.en
dc.description.affiliationDepto. de Clín. Médica Ctro. de Cie. da Saúde Universidade Estadual de Londrina, Londrina, PR
dc.description.affiliationLab. Bioquim. Nutricional Metabolica Depto. de Clín. Médica Univ. Estadual Paulista - UNESP, Botucatu, SP
dc.description.affiliationLab. de Análise de Alimentos Departamento de Medicina Legal Faculdade Med. de Botucatu - UNESP
dc.description.affiliationDepartamento de Patologia Faculdade de Medicina de Botucatu UNESP
dc.description.affiliationDepto. de Clín. Médica Faculdade de Medicina de Botucatu UNESP
dc.description.affiliationDepto. de Clín. Médica Ctro. de Cie. da Saúde Universidade Estadual de Londrina, 86038-440 - Londrina, PR
dc.description.affiliationUnespLab. Bioquim. Nutricional Metabolica Depto. de Clín. Médica Univ. Estadual Paulista - UNESP, Botucatu, SP
dc.description.affiliationUnespLab. de Análise de Alimentos Departamento de Medicina Legal Faculdade Med. de Botucatu - UNESP
dc.description.affiliationUnespDepartamento de Patologia Faculdade de Medicina de Botucatu UNESP
dc.description.affiliationUnespDepto. de Clín. Médica Faculdade de Medicina de Botucatu UNESP
dc.format.extent175-180
dc.identifier.citationArquivos de Gastroenterologia, v. 35, n. 3, p. 175-180, 1998.
dc.identifier.issn0004-2803
dc.identifier.lattes2287552780901172
dc.identifier.scopus2-s2.0-8744300937
dc.identifier.urihttp://hdl.handle.net/11449/65650
dc.language.isopor
dc.relation.ispartofArquivos de Gastroenterologia
dc.relation.ispartofsjr0,396
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectColitis, ulcerative
dc.subjectProteins, biosynthesis
dc.subjectProteins, metabolism
dc.subjectglycine
dc.subjectprotein
dc.subjectfemale
dc.subjecthospitalization
dc.subjecthuman
dc.subjectmale
dc.subjectmetabolism
dc.subjectmiddle aged
dc.subjectulcerative colitis
dc.subjectColitis, Ulcerative
dc.subjectFemale
dc.subjectGlycine
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectProteins
dc.subjectSeverity of Illness Index
dc.titleUtilização do metabolismo protéico ( 15N-glicina) na detecção precoce de agravamento da atividade da doença em pacientes portadores de retocolite ulcerativa inespecíficapt
dc.title.alternativePrecocious detection of disease exacerbation in ulcerative colitis patients using kinetic study with 15N-glycineen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/ag/paboutj.htm
unesp.author.lattes2287552780901172
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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