Taenia solium DNA is present in the cerebrospinal fluid of neurocysticercosis patients and can be used for diagnosis

Página do item simplificado
dc.contributor.authorAlmeida, Carolina R.
dc.contributor.authorOjopi, Elida P.
dc.contributor.authorNunes, Caris Maroni [UNESP]
dc.contributor.authorMachado, Luis R.
dc.contributor.authorTakayanagui, Osvaldo M.
dc.contributor.authorLivramento, Jose A.
dc.contributor.authorAbraham, Ronaldo
dc.contributor.authorGattaz, Wagner F.
dc.contributor.authorVaz, Adelaide J.
dc.contributor.authorDias-Neto, Emmanuel
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Taubate
dc.date.accessioned2014-02-26T17:26:11Z
dc.date.accessioned2014-05-20T13:42:19Z
dc.date.available2014-02-26T17:26:11Z
dc.date.available2014-05-20T13:42:19Z
dc.date.issued2006-08-01
dc.description.abstractNeurocysticercosis is the most frequent parasitic infection of the CNS and the main cause of acquired epilepsy worldwide. Seizures are the most common symptoms of the disease, together with headache, involuntary movements, psychosis and a global mental deterioration. Absolute diagnostic criteria include the identification of cysticerci, with scolex, in the brain by MRI imaging. We demonstrate here, for the first time, that T. solium DNA is present in the cerebrospinal fluid of patients. The PCR amplification of the parasite DNA in the CSF enabled the correct identification of 29/30 cases (96.7 %). The PCR diagnosis of parasite DNA in the CSF may be a strong support for the diagnosis of neurocysticercosis.en
dc.description.affiliationUniv São Paulo, Fac Med, Inst Psiquiatria, Lab Neurociencias, BR-05403010 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Fac Med, Dept Psiquiatria, BR-05403010 São Paulo, Brazil
dc.description.affiliationUNESP, Dept Apoio Prod & Saúde Anim, Aracatuba, SP, Brazil
dc.description.affiliationUniv São Paulo, FMUSP, Dept Neurol, BR-05403010 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Fac Med Ribeirao Preto, Dept Neurol, BR-14048900 Ribeirao Preto, SP, Brazil
dc.description.affiliationUniv Taubate, Dept Med, Taubate, SP, Brazil
dc.description.affiliationUSP, Fac Ciências Farmaceut, Lab Imunol Clin, BR-09500900 São Paulo, Brazil
dc.description.affiliationUnespUNESP, Dept Apoio Prod & Saúde Anim, Aracatuba, SP, Brazil
dc.format.extent307-310
dc.identifierhttp://dx.doi.org/10.1007/s00406-006-0612-3
dc.identifier.citationEuropean Archives of Psychiatry and Clinical Neuroscience. Darmstadt: Dr Dietrich Steinkopff Verlag, v. 256, n. 5, p. 307-310, 2006.
dc.identifier.doi10.1007/s00406-006-0612-3
dc.identifier.issn0940-1334
dc.identifier.lattes1892359871207408
dc.identifier.urihttp://hdl.handle.net/11449/14719
dc.identifier.wosWOS:000240017400008
dc.language.isoeng
dc.publisherDr Dietrich Steinkopff Verlag
dc.relation.ispartofEuropean Archives of Psychiatry and Clinical Neuroscience
dc.relation.ispartofjcr3.617
dc.relation.ispartofsjr1,574
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectPCRpt
dc.subjectCSFpt
dc.subjectneurocysticercosispt
dc.subjectTaenia soliumpt
dc.subjectliquorpt
dc.titleTaenia solium DNA is present in the cerebrospinal fluid of neurocysticercosis patients and can be used for diagnosisen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights
dcterms.rightsHolderDr Dietrich Steinkopff Verlag
unesp.author.lattes1892359871207408[3]
unesp.author.orcid0000-0002-8190-0275[5]
unesp.author.orcid0000-0001-5824-5199[2]
unesp.author.orcid0000-0001-5670-8559[10]
unesp.author.orcid0000-0002-5463-3845[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária, Araçatubapt

Arquivos

Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Apoio, Produção e Saúde Animal - FMVA