On the effect of aromatherapy with citrus fragrance in the therapy of major depressive disorder

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dc.contributor.authorPereira, Maria Alice Ornellas [UNESP]
dc.contributor.authorPereira Jr., Alfredo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-04-01T18:43:15Z
dc.date.available2016-04-01T18:43:15Z
dc.date.issued2014
dc.description.abstractThe effect of aromatherapy on the human central nervous system is a controversial issue in medical sciences. Here we present a hypothesis relating citrus fragrance aromatherapy with brain glucose homeostasis in Major Depressive Disorder. How to conciliate the correlation between depression and resistance to insulin with the fact that glucose transport to neurons is not made directly by insulin? We briefly discuss the mechanism of dynamical glucose balance in the brain, which includes lactate transport from astrocytes to neuronal mitochondria supporting ATP (and then cAMP) production. We hypothesize that odors like vanillin and citrus fragrances fool the brain’s glucose level sensors, reducing the subjective feeling of "low energy". This hypothesis can help to explain the surprisingly positive results found in the treatment of depression with aromatherapy.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Enfermagem, Botucatu, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Enfermagem, Botucatu, SP, Brasil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent1-3
dc.identifierhttp://dx.doi.org/10.4172/2161-0487.1000169
dc.identifier.citationJournal of Psychology and Psychotherapy, v. 5, n. 1, p. 1-3, 2014.
dc.identifier.doi10.4172/2161-0487.1000169
dc.identifier.fileISSN2161-0487-2014-05-01-01-03.pdf
dc.identifier.issn2161-0487
dc.identifier.orcid0000-0002-5960-041X
dc.identifier.urihttp://hdl.handle.net/11449/136910
dc.language.isoeng
dc.relation.ispartofJournal of Psychology and Psychotherapy
dc.rights.accessRightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectDepressionen
dc.subjectGlucoseen
dc.subjectLactateen
dc.subjectBrain homeostasisen
dc.subjectReward systemen
dc.subjectAromatherapyen
dc.titleOn the effect of aromatherapy with citrus fragrance in the therapy of major depressive disorderen
dc.typeArtigo
unesp.author.orcid0000-0002-5960-041X[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.departmentEnfermagempt

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