Bullosis diabeticorum as a differential diagnosis for limb ulcers: case report

Página do item simplificado
dc.contributor.authorGrillo, Vinicius Tadeu Ramos da Silva [UNESP]
dc.contributor.authorBotelho, Mayra Souza [UNESP]
dc.contributor.authorLange, Eloana Pasqualin [UNESP]
dc.contributor.authorSecanho, Murilo Sgarbi [UNESP]
dc.contributor.authorde Camargo, Paula Angeleli Bueno [UNESP]
dc.contributor.authorMiot, Hélio Amante [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T14:03:24Z
dc.date.available2023-07-29T14:03:24Z
dc.date.issued2022-01-01
dc.description.abstractBullosis diabeticorum (BD) is an uncommon cutaneous manifestation of diabetes that can affect the upper limbs. It is characterized by spontaneous and painless non-inflammatory bloody blisters, which can progress to necrosis, requiring differential diagnosis to rule out other dermatological diseases, such as porphyria cutanea tarda, pseudoporphyria, epidermolysis bullosa acquisita, and pemphigoid, and vascular diseases, such as vasculitis, peripheral arterial disease, and Buerger’s disease, among others. In this report, we describe a 77-year-old male patient with poorly controlled diabetes and hypertension who presented with spontaneous onset of lesions on the upper limbs, initially with bullous characteristics, progressing to necrotic ulcers after spontaneous rupture. A biopsy revealed hyaline thickening of the dermal vessels and subcorneal bullae, consistent with a diagnosis of BD. After smoking cessation and optimization of glycemia control combined with topical corticosteroid therapy, the condition improved and lesions began to heal. This presentation of BD involving the upper limbs is rare, requiring differential diagnosis to rule out other cutaneous and vascular lesions.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho – UNESP Faculdade de Medicina, Campus de Botucatu, SP
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho – UNESP Faculdade de Medicina, Campus de Botucatu, SP
dc.identifierhttp://dx.doi.org/10.1590/1677-5449.202101901
dc.identifier.citationJornal Vascular Brasileiro, v. 21.
dc.identifier.doi10.1590/1677-5449.202101901
dc.identifier.issn1677-7301
dc.identifier.issn1677-5449
dc.identifier.scopus2-s2.0-85137664821
dc.identifier.urihttp://hdl.handle.net/11449/249135
dc.language.isopor
dc.relation.ispartofJornal Vascular Brasileiro
dc.sourceScopus
dc.subjectblister
dc.subjectbullosis diabeticorum
dc.subjectcase report
dc.subjectdiabetes complications
dc.subjectskin ulcer
dc.titleBullosis diabeticorum as a differential diagnosis for limb ulcers: case reporten
dc.titleBullosis diabeticorum como diagnóstico diferencial de úlcera de membros: relato de casopt
dc.typeArtigo

Arquivos

Coleções

Artigos - Dermatologia e Radioterapia - FMB