Bioactive glass added to autogenous bone graft in maxillary sinus augmentation: a prospective histomorphometric, immunohistochemical, and bone graft resorption assessment

Página do item simplificado
dc.contributor.authorMenezes, Juliana Dreyer [UNESP]
dc.contributor.authorPereira, Rodrigo dos Santos [UNESP]
dc.contributor.authorBonardi, Joao Paulo [UNESP]
dc.contributor.authorGriza, Geraldo Luiz [UNESP]
dc.contributor.authorOkamoto, Roberta [UNESP]
dc.contributor.authorHochuli-Vieira, Eduardo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2020-12-10T19:47:02Z
dc.date.available2020-12-10T19:47:02Z
dc.date.issued2018-01-01
dc.description.abstractObjective: The aim of this study was to compare the bone resorption rate, histomorphometry and immunohistochemical findings of bioactive glass (Biogran; Biomet, Warsaw, IN, USA) mixed with autogenous bone grafts (1:1) and autogenous bone graft isolate in maxillary sinus elevation surgery. Material and Methods: A total of 9 maxillary sinuses were grafted with Biogran with autogenous bone graft (group 1) and 12 were mixed with autogenous bone graft (group 2). Postoperative cone beam computed tomography (CBCT) was used to measure the initial graft volume after 15 days (T1), and 6 months later, another CBCT scan was performed to evaluate the final graft volume (T2) and determine the graft resorption rate. The resorption outcomes were 37.9%+/- 18.9% in group 1 and 45.7%+/- 18.5% in group 2 (P=0.82). After 6 months, biopsies were obtained concurrent with the placement of dental implants; these implants were subjected to histomorphometric analysis and immunohistochemical analysis for tartrate-resistant acid phosphatase (TRAP). Results: The average bone formation in group 1 was 36.6%+/- 12.9 in the pristine bone region, 33.2%+/- 13.3 in the intermediate region, and 45.8%+/- 13.8 in the apical region; in group 2, the values were 34.4%+/- 14.4, 35.0%+/- 13.9, and 42.0%+/- 16.6 of new bone formation in the pristine bone, intermediate, and apical regions, respectively. Immunostaining for TRAP showed poor clastic activity in both groups, which can indicate that those were in the remodeling phase. Conclusions: The similarity between the groups in the formation and maintenance of the graft volume after 6 months suggests that the bioactive glass mixed with autogenous bone (1:1) can be used safely as a bone substitute for the maxillary sinus lift.en
dc.description.affiliationUniv Estadual Paulista, Fac Odontol Araraquara, Araraquara, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Odontol Aracatuba, Aracatuba, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Odontol Aracatuba, Dept Ciencias Bas, Aracatuba, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Odontol Aracatuba, Dept Cirurgia Diagnost, Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol Araraquara, Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol Aracatuba, Aracatuba, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol Aracatuba, Dept Ciencias Bas, Aracatuba, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol Aracatuba, Dept Cirurgia Diagnost, Araraquara, SP, Brazil
dc.format.extent9
dc.identifierhttp://dx.doi.org/10.1590/1678-7757-2017-0296
dc.identifier.citationJournal Of Applied Oral Science. Bauru-sp: Univ Sao Paulo Fac Odontologia Bauru, v. 26, 9 p., 2018.
dc.identifier.doi10.1590/1678-7757-2017-0296
dc.identifier.fileS1678-77572018000100460.pdf
dc.identifier.issn1678-7757
dc.identifier.scieloS1678-77572018000100460
dc.identifier.urihttp://hdl.handle.net/11449/196504
dc.identifier.wosWOS:000507907400001
dc.language.isoeng
dc.publisherUniv Sao Paulo Fac Odontologia Bauru
dc.relation.ispartofJournal Of Applied Oral Science
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectMaxillary sinus
dc.subjectBone graft
dc.subjectImmunohistochemistry
dc.titleBioactive glass added to autogenous bone graft in maxillary sinus augmentation: a prospective histomorphometric, immunohistochemical, and bone graft resorption assessmenten
dc.typeArtigo
dcterms.rightsHolderUniv Sao Paulo Fac Odontologia Bauru
unesp.author.orcid0000-0003-2509-8633[2]
unesp.author.orcid0000-0002-6773-6966[5]
unesp.author.orcid0000-0003-4040-9313[6]

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
S1678-77572018000100460.pdf
Tamanho:
3.04 MB
Formato:
Adobe Portable Document Format
Baixar

Coleções

Artigos - Diagnóstico e Cirurgia - FOAR