CELL-WALL FRACTIONS FROM PARACOCCIDIOIDES-BRASILIENSIS INDUCE HYPERGAMMAGLOBULINEMIA

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dc.contributor.authorDeoliveira, S. L.
dc.contributor.authorDasilva, M. F.
dc.contributor.authorSoares, AMVD
dc.contributor.authorSilva, C. L.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2020-12-10T20:12:09Z
dc.date.available2020-12-10T20:12:09Z
dc.date.issued1993-01-01
dc.description.abstractThe antibody response against the antigen sheep red blood cells (SRBC) was investigated in mice pre-treated with formalin-killed Paracoccidioides brasiliensis or with cell wall fractions of the fungus. Pre-treatment with P. brasiliensis, as well as with the F1 fraction and beta-glucan significantly increased the anti-SRBC antibody response in the experimental groups as compared to the control group that received only SRBC. This immunomodulatory effect varied with the different doses employed and with pre-treatment time. We conclude that the cell wall fractions of P. brasiliensis might play an important role in the hypergammaglobulinemia associated with Paracoccidioidomycosis.en
dc.description.affiliationUNIV SAO PAULO, SCH MED RIBEIRAO PRETO, DEPT PARASITOL MICROBIOL & IMMUNOL, BR-14049 RIBEIRAO PRETO, SP, BRAZIL
dc.description.affiliationUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO, DEPT MICROBIOL & IMMUNOL, BOTUCATU, SP, BRAZIL
dc.description.affiliationUnespUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO, DEPT MICROBIOL & IMMUNOL, BOTUCATU, SP, BRAZIL
dc.format.extent1-5
dc.identifier.citationMycopathologia. Dordrecht: Springer, v. 121, n. 1, p. 1-5, 1993.
dc.identifier.issn0301-486X
dc.identifier.urihttp://hdl.handle.net/11449/197287
dc.identifier.wosWOS:A1993KK24300001
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofMycopathologia
dc.sourceWeb of Science
dc.subjectBETA-GLUCAN
dc.subjectCELL WALL
dc.subjectHYPERGAMMAGLOBULINEMIA
dc.subjectPARACOCCIDIOIDOMYCOSIS
dc.subjectPARACOCCIDIOIDES-BRASILIENSIS
dc.titleCELL-WALL FRACTIONS FROM PARACOCCIDIOIDES-BRASILIENSIS INDUCE HYPERGAMMAGLOBULINEMIAen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer

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Artigos - Microbiologia e Imunologia - IBB