Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth.

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dc.contributor.authorMigliato, K. F. [UNESP]
dc.contributor.authorChorilli, Marlus [UNESP]
dc.contributor.authorScarpa, M. V. [UNESP]
dc.contributor.authorMoreira, Raquel Regina Duarte [UNESP]
dc.contributor.authorCorrea, Marcos Antonio [UNESP]
dc.contributor.authorIsaac, Vera Lucia Borges [UNESP]
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:54Z
dc.date.available2014-05-27T11:23:54Z
dc.date.issued2009-05-01
dc.description.abstractDimorphandra mollis Benth., Compositae, false barbatimão, has been used topically as a healing, astringent and antibacterial. In this study, antibacterial activity was verified on liquid soap containing glycolic extract of D. mollis (DGE) at different concentrations (8, 15 and 20%) and at different pH levels (6 and 8). Five soap formulations (F) were prepared: F1 - tryclosan (0.1%), F2 - DGE (8%), F3 - DGE (15%), F4 - DGE (20%) and F5 - without preservatives. Bark of D. mollis were dried in a circulating air oven and ground. The rude extracts were prepared by turbo extraction with ethanol. After screening, the extract were concentrated in rotating evaporator, lyophilized and resuspended in propileneglycol to obtain the glycolic extract. The antimicrobial activity was verified by diffusion in agar method, using cylinder in plate. Plates containing Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli were incubated at 37°C for 24 hours. After incubation, the results were analysed with a pachymeter, observing the bacterial grouth inhibition halo diameter. It was verified that the liquid soap containing tryclosan caused on inhibition of bacterial growth at both pH levels; the soaps without preservatives and containing DGE, independently of the concentration and pH levels used, did not present antibacterial activity.en
dc.description.affiliationDepartamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas de Araraquara UNESP, Rodovia Araraquara-Jaú, km 1, CEP: 14801-902 - Araraquara - SP
dc.description.affiliationDepartamento de Princípios Ativos Naturais e Toxicologia Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, UNESP, Araraquara, SP
dc.description.affiliationUnespDepartamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas de Araraquara UNESP, Rodovia Araraquara-Jaú, km 1, CEP: 14801-902 - Araraquara - SP
dc.description.affiliationUnespDepartamento de Princípios Ativos Naturais e Toxicologia Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, UNESP, Araraquara, SP
dc.format.extent197-202
dc.identifierhttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/1072
dc.identifier.citationRevista de Ciencias Farmaceuticas Basica e Aplicada, v. 30, n. 2, p. 197-202, 2009.
dc.identifier.file2-s2.0-78649896459.pdf
dc.identifier.issn1808-4532
dc.identifier.issn2179-443X
dc.identifier.lattes3316011688829943
dc.identifier.lattes4842462513285606
dc.identifier.lattes1427125996716282
dc.identifier.lattes7710344461864924
dc.identifier.orcid0000-0002-4253-0320
dc.identifier.scopus2-s2.0-78649896459
dc.identifier.urihttp://hdl.handle.net/11449/70998
dc.language.isopor
dc.relation.ispartofRevista de Ciências Farmacêuticas Básica e Aplicada
dc.relation.ispartofsjr0,131
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAntibacterial activity
dc.subjectDimorphandra mollis Benth.
dc.subjectLiquid soap
dc.subjectantiinfective agent
dc.subjectdimorphandra mollis extract
dc.subjectglycolic acid
dc.subjectplant extract
dc.subjectpreservative
dc.subjectsoap
dc.subjectunclassified drug
dc.subjectagar diffusion
dc.subjectantibacterial activity
dc.subjectbacterial growth
dc.subjectbark
dc.subjectconcentration (parameters)
dc.subjectdimorphandra mollis
dc.subjectdrug inhibition
dc.subjectEscherichia coli
dc.subjectgrowth inhibition
dc.subjectincubation temperature
dc.subjectmedicinal plant
dc.subjectnonhuman
dc.subjectpH
dc.subjectPseudomonas aeruginosa
dc.subjectStaphylococcus aureus
dc.titleVerificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth.pt
dc.title.alternativeVerification of the antibacterial activity of liquid soap containing glycolic extract of Dimorphandra mollis Benth.en
dc.typeArtigo
dcterms.licensehttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/about
unesp.author.lattes3316011688829943
unesp.author.lattes4842462513285606
unesp.author.lattes1427125996716282
unesp.author.lattes7710344461864924[4]
unesp.author.orcid0000-0002-4253-0320[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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Artigos - Fármacos e Medicamentos - FCFAR
Artigos - Princípios Ativos Naturais e Toxicologia - FCFAR