Perioperative administration of vedaprofen, tramadol or their combination does not interfere with platelet aggregation, bleeding time and biochemical variables in cats

Página do item simplificado
dc.contributor.authorBrondani, Juliana T. [UNESP]
dc.contributor.authorLuna, Stelio P. L. [UNESP]
dc.contributor.authorMarcello, Gracy C. G. [UNESP]
dc.contributor.authorPadovani, Carlos R. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:33:10Z
dc.date.available2014-05-20T15:33:10Z
dc.date.issued2009-06-01
dc.description.abstractA randomized double blind and placebo controlled design was used to investigate the hemostatic, biochemical, gastrointestinal and behavioral effects of pre- and postoperative administration of vedaprofen 0.5 mg/kg PO (V), tramadol 2 mg/kg SC (T), their association (VT) or placebo (P) in 40 adult female cats (3.0 +/- 0.32 kg; 1.8 +/- 0.7 years) distributed in groups of 10. Platelet aggregation and bleeding time were measured before and 52 11 after ovariohysterectomy. Serum urea, creatinine, alanine aminotransferase, alkaline phosphatase and gamma-glutamyl transferase concentrations were measured before and 7 days postoperatively. The occurrence of vomiting, frequency and consistency of feces, and behavior were observed for 7 days postoperatively. Morphine (0.5 mg/kg, IM) was used as rescue analgesic. Laboratory variables did not change. Vomiting was observed only after morphine administration. Mild euphoria was observed in T and VT. The perioperative use of vedaprofen and/or tramadol did not modify the hemostatic, biochemical and gastrointestinal function in cats. (C) 2009 ESFM and AAFP. published by Elsevier Ltd. All rights reserved.en
dc.description.affiliationSão Paulo State Univ, Sch Vet Med & Anim Sci, Dept Vet Surg & Anesthesiol, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Inst Biosci, Dept Biostat, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Sch Vet Med & Anim Sci, Dept Vet Surg & Anesthesiol, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Inst Biosci, Dept Biostat, São Paulo, Brazil
dc.format.extent503-509
dc.identifierhttp://dx.doi.org/10.1016/j.jfms.2008.12.003
dc.identifier.citationJournal of Feline Medicine and Surgery. Oxford: Elsevier B.V., v. 11, n. 6, p. 503-509, 2009.
dc.identifier.doi10.1616/j.jfms.2008.12.003
dc.identifier.issn1098-612X
dc.identifier.orcid0000-0001-5312-9076
dc.identifier.urihttp://hdl.handle.net/11449/41870
dc.identifier.wosWOS:000267109400015
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Feline Medicine and Surgery
dc.relation.ispartofjcr1.466
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titlePerioperative administration of vedaprofen, tramadol or their combination does not interfere with platelet aggregation, bleeding time and biochemical variables in catsen
dc.typeTrabalho apresentado em evento
dcterms.licensehttp://www.uk.sagepub.com/aboutus/openaccess.htm
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes8727897080522289[4]
unesp.author.orcid0000-0002-7719-9682[4]
unesp.author.orcid0000-0001-5312-9076[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

Arquivos

Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Bioestatística - IBB