Case study of two post vaccination SARS-CoV-2 infections with P1 variants in coronavac vaccinees in Brazil
dc.contributor.author | Estofolete, Cassia F. | |
dc.contributor.author | Banho, Cecilia A. | |
dc.contributor.author | Campos, Guilherme R.F. | |
dc.contributor.author | Marques, Beatriz C. | |
dc.contributor.author | Sacchetto, Livia | |
dc.contributor.author | Ullmann, Leila S. [UNESP] | |
dc.contributor.author | Possebon, Fabio S. [UNESP] | |
dc.contributor.author | Machado, Luana F. | |
dc.contributor.author | Syrio, Juliana D. | |
dc.contributor.author | Araújo Junior, João P. [UNESP] | |
dc.contributor.author | Bittar, Cintia [UNESP] | |
dc.contributor.author | Rahal, Paula [UNESP] | |
dc.contributor.author | Lobo, Suzana M.A. | |
dc.contributor.author | Ferreira, Helena Lage | |
dc.contributor.author | Vasilakis, Nikos | |
dc.contributor.author | Nogueira, Mauricio L. | |
dc.contributor.institution | Medicine School of São José do Rio Preto (FAMERP) | |
dc.contributor.institution | Hospital de Base | |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.contributor.institution | University of Texas Medical Branch | |
dc.date.accessioned | 2022-05-01T06:02:16Z | |
dc.date.available | 2022-05-01T06:02:16Z | |
dc.date.issued | 2021-07-01 | |
dc.description.abstract | The rapid development of efficacious and safe vaccines against coronavirus disease 2019 (COVID-19) has been instrumental in mitigating the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Moreover, the emergence of SARS-CoV-2 variants raised concerns on the efficacy of these vaccines. Herein, we report two cases of breakthrough infections with the P1 variant in patients vaccinated with CoronaVac, which is one of the two vaccines authorized for emergency use in the Brazilian immunization program. Our observations suggest that the vaccine reduced the severity of the disease and highlight the potential risk of illness following vaccination and subsequent infection with the P1 variant as well as for continued efforts to prevent and diagnose infection in vaccinated persons. | en |
dc.description.affiliation | Laboratório de Pesquisas em Virologia (LPV) Medicine School of São José do Rio Preto (FAMERP) | |
dc.description.affiliation | Hospital de Base | |
dc.description.affiliation | Biotecnology Institute São Paulo State University (UNESP) | |
dc.description.affiliation | Intitute of Biosciences Languages and Exact Sciences São Paulo State University (UNESP) | |
dc.description.affiliation | Department of Veterinary Medicine FZEA-USP University of São Paulo (USP) | |
dc.description.affiliation | Department of Pathology University of Texas Medical Branch, 301 University Blvd | |
dc.description.affiliation | Sealy Center for Vector-Borne and Zoonotic Diseases University of Texas Medical Branch, 301 University Blvd | |
dc.description.affiliation | Center for Biodefense and Emerging Infectious Diseases University of Texas Medical Branch, 301 University Blvd | |
dc.description.affiliation | Center for Tropical Diseases University of Texas Medical Branch, 301 University Blvd | |
dc.description.affiliation | Institute for Human Infection and Immunity University of Texas Medical Branch, 301 University Blvd | |
dc.description.affiliationUnesp | Biotecnology Institute São Paulo State University (UNESP) | |
dc.description.affiliationUnesp | Intitute of Biosciences Languages and Exact Sciences São Paulo State University (UNESP) | |
dc.identifier | http://dx.doi.org/10.3390/v13071237 | |
dc.identifier.citation | Viruses, v. 13, n. 7, 2021. | |
dc.identifier.doi | 10.3390/v13071237 | |
dc.identifier.issn | 1999-4915 | |
dc.identifier.scopus | 2-s2.0-85109565185 | |
dc.identifier.uri | http://hdl.handle.net/11449/233252 | |
dc.language.iso | eng | |
dc.relation.ispartof | Viruses | |
dc.source | Scopus | |
dc.subject | COVID-19 | |
dc.subject | SARS-CoV-2 | |
dc.subject | Vaccine | |
dc.title | Case study of two post vaccination SARS-CoV-2 infections with P1 variants in coronavac vaccinees in Brazil | en |
dc.type | Artigo | |
unesp.author.orcid | 0000-0001-7324-1591 0000-0001-7324-1591[1] | |
unesp.author.orcid | 0000-0001-5090-1534[2] | |
unesp.author.orcid | 0000-0003-1118-8486[3] | |
unesp.author.orcid | 0000-0001-9716-6899[5] | |
unesp.author.orcid | 0000-0002-0118-6164[7] | |
unesp.author.orcid | 0000-0002-9153-1485[10] | |
unesp.author.orcid | 0000-0002-2048-4589[11] | |
unesp.author.orcid | 0000-0003-2726-2441[13] | |
unesp.author.orcid | 0000-0002-3261-3712[14] | |
unesp.author.orcid | 0000-0002-0708-3289 0000-0002-0708-3289 0000-0002-0708-3289 0000-0002-0708-3289 0000-0002-0708-3289[15] |