Serologic profile in hepatitis B virus and hepatitis C virus in a Brazilian liver transplant waiting list

Página do item simplificado
dc.contributor.authorAlmeida, R. A. M. B.
dc.contributor.authorSilva, G. F.
dc.contributor.authorLlanos, J. C.
dc.contributor.authorWinckler, C. C.
dc.contributor.authorGomes, M. R. B.
dc.contributor.authorBiagioni, D. S.
dc.contributor.authorPaula, R. C. C.
dc.contributor.authorMeira, D. A.
dc.contributor.authorBakonyi, A.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:28:33Z
dc.date.available2014-05-20T15:28:33Z
dc.date.issued2006-07-01
dc.description.abstractChronic viral hepatitis is currently the most common indication for liver transplantation (OLT). Knowing the serological profile of patients on the liver transplant waiting list (LTWL) is essential to manage prophylactic and therapeutic strategies pre- and post-OLT. The aim of this study was to determine the hepatitis B virus (HBV) and hepatitis C virus (HCV) serological profile on the LTWL.Methods. Serological data were collected from 44 candidates included on, the LTWL from May 2003 to November 2004. HBV and HCV serological profiles were performed by microenzyme immunoassay.Results. Twenty-eight patients (66.7%) lacked H13V serological markers. Anti-HBs was detected in 9.5% and was positive for HBsAg, anti-HBc, IgM anti-HBc, or HbeAg in 4.8% of patients, probably related to reactivation of chronic infection. In 7.1% of patients, the markers demonstrated serological cure of infection. In HCV patients, 41.5% were positive. There was H13V and HCV co-infection in 12.2% of patients.Conclusion. HBV infection in 21.4% of the patients corroborates the need to use more efficient protocols for prophylactic and therapeutic management pre- and post-OLT. The high prevalence of HCV infection reinforces the need to follow adequate protocols to avoid related complications and guarantee rational and universal use of more efficient drugs.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Botucatu Sch Med, Hosp Clin, Div Liver & Pancreas Transplantat, BR-18603310 Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Botucatu Sch Med, Hosp Clin, Div Liver & Pancreas Transplantat, BR-18603310 Botucatu, SP, Brazil
dc.format.extent1920-1921
dc.identifierhttp://dx.doi.org/10.1016/j.transproceed.2006.06.060
dc.identifier.citationTransplantation Proceedings. New York: Elsevier B.V., v. 38, n. 6, p. 1920-1921, 2006.
dc.identifier.doi10.1016/j.transproceed.2006.06.060
dc.identifier.issn0041-1345
dc.identifier.urihttp://hdl.handle.net/11449/38348
dc.identifier.wosWOS:000240051700086
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofTransplantation Proceedings
dc.relation.ispartofjcr0.806
dc.relation.ispartofsjr0,422
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleSerologic profile in hepatitis B virus and hepatitis C virus in a Brazilian liver transplant waiting listen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.

Arquivos

Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Hospital das Clínicas (HC) - Botucatu