AORTIC BARORECEPTORS PLAY A PREDOMINANT ROLE IN THE REGULATION OF HINDLIMB VASCULAR-RESISTANCE IN RATS

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dc.contributor.authorMachado, B. H.
dc.contributor.authorBonagamba, LGH
dc.contributor.authorCastania, J. A.
dc.contributor.authorMenani, José Vanderlei [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:25:01Z
dc.date.available2014-05-20T15:25:01Z
dc.date.issued1994-08-01
dc.description.abstractIn previous studies using bilateral carotid occlusion in conscious freely moving rats we suggested that aortic baroreceptors may play a more important role in the regulation of hindlimb than in renal and mesenteric vascular resistances. In the present study we performed electrical stimulation of the aortic baroreceptor nerve and analyzed the changes in mean arterial pressure and in hindlimb, renal, and mesenteric vascular resistances. All the experiments were performed under urethan anesthesia. Unilateral electrical stimulation (3 V, 2 ms, 50 Hz) of the aortic baroreceptor nerve produced a fall in arterial pressure (-27 +/- 3 mmHg) and an important reduction in hindlimb vascular resistance (-43 +/- 5%), with an increase in renal (+3 +/- 14%) and mesenteric (+48 +/- 12%) vascular resistances. Similar changes in arterial pressure as well as in the resistance of the three vascular beds studied were also observed during electrical stimulation of the aortic baroreceptor nerve in rats with bilateral carotid baroreceptor denervation or in rats treated with methylatropine. The data obtained with electrical stimulation indicated that aortic baroreceptors play a more important role in the regulation of blood flow in hindlimb than in renal and mesenteric vascular beds.en
dc.description.affiliationPAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,BR-14801903 SAO PAULO,BRAZIL
dc.description.affiliationUnespPAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,BR-14801903 SAO PAULO,BRAZIL
dc.format.extentR476-R480
dc.identifierhttp://ajpregu.physiology.org/content/267/2/R476
dc.identifier.citationAmerican Journal of Physiology. Bethesda: Amer Physiological Soc, v. 267, n. 2, p. R476-R480, 1994.
dc.identifier.issn0002-9513
dc.identifier.lattes1023597870118105
dc.identifier.urihttp://hdl.handle.net/11449/35495
dc.identifier.wosWOS:A1994PC44100072
dc.language.isoeng
dc.publisherAmer Physiological Soc
dc.relation.ispartofAmerican Journal of Physiology
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectCARDIOVASCULAR REGULATIONpt
dc.subjectBLOOD FLOWpt
dc.subjectBAROREFLEXpt
dc.subjectCAROTID BARORECEPTORSpt
dc.titleAORTIC BARORECEPTORS PLAY A PREDOMINANT ROLE IN THE REGULATION OF HINDLIMB VASCULAR-RESISTANCE IN RATSen
dc.typeArtigo
dcterms.licensehttp://www.the-aps.org/mm/Publications/Info-For-Authors/Copyright
dcterms.rightsHolderAmer Physiological Soc
unesp.author.lattes1023597870118105
unesp.author.orcid0000-0003-1167-4441[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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