Development and analysis of formulations to the delivery of caffeine for the treatment of gynoid lipodystrophy

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dc.contributor.authorIsaac, Vera Lucia Borges [UNESP]
dc.contributor.authorChiari, Bruna Galdorfini
dc.contributor.authorBoschetti, Viviane Cristine
dc.contributor.authorUema, Marisa Keiko
dc.contributor.authorAlmeida, Maria Gabriela José de
dc.contributor.authorCorrêa, Marcos Antonio
dc.contributor.authorKedor-Hackmann, Erika Rosa Maria
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-01-28T16:57:11Z
dc.date.available2016-01-28T16:57:11Z
dc.date.issued2014
dc.description.abstractThis study aimed to investigate the kinetics of the in vitro release of caffeine in various excipients, and to perform the rheological characterization of these excipients. In vitro release experiments were performed using cellulose membranes in a diffusion apparatus adapted. In order to characterize the rheological behavior of the excipients, a viscometer was used to obtain the flow curves. The data obtained in the present study suggest that caffeine release from the various excipients is dependent of the solubility of caffeine in the excipient (or in the phase of the excipient where caffeine were solubilized) and of the rheological features, mainly the viscosity.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km 1, Câmpus Universitário, CEP 14800-850, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km 1, Câmpus Universitário, CEP 14800-850, SP, Brasil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent14-20
dc.identifierhttp://sciipub.com/media/kunena/attachments/62/IJDDS-2.pdf
dc.identifier.citationInternational Journal of Drug Delivery Science, v. 1, n. 1, p. 14-20, 2014.
dc.identifier.issn2278-4225
dc.identifier.lattes7579189327299923
dc.identifier.lattes4842462513285606
dc.identifier.lattes6153974945085893
dc.identifier.lattes3316011688829943
dc.identifier.urihttp://hdl.handle.net/11449/133929
dc.language.isoeng
dc.relation.ispartofInternational Journal of Drug Delivery Science
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.subjectCaffeineen
dc.subjectExcipienten
dc.subjectGynoide lipodystrophyen
dc.subjectIn vitro releaseen
dc.titleDevelopment and analysis of formulations to the delivery of caffeine for the treatment of gynoid lipodystrophyen
dc.typeArtigo
unesp.author.lattes7579189327299923
unesp.author.lattes4842462513285606
unesp.author.lattes6153974945085893
unesp.author.lattes3316011688829943
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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