Effect of induced diabetes mellitus on alveolar bone loss after 30 days of ligature-induced periodontal disease

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dc.contributor.authorGomes, Débora Aline Silva
dc.contributor.authorSpolidório, Denise Madalena Palomari [UNESP]
dc.contributor.authorPepato, Maria Teresa
dc.contributor.authorZuza, Elizangela Partata
dc.contributor.authorde Toledo, Benedicto Egbert Corrêa
dc.contributor.authorGonçalves, Andréa [UNESP]
dc.contributor.authorSpolidório, Luis Carlos [UNESP]
dc.contributor.authorPires, Juliana Rico
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:53Z
dc.date.available2014-05-27T11:23:53Z
dc.date.issued2009-04-01
dc.description.abstractSeveral studies have shown that diabetics are more susceptible to the development of severe periodontal disease. Currently, the use of animal models can be considered a feasible alternative in radiographic assessments of these two pathologies. The purpose of this radiographic study was to evaluate the effect of induced diabetes mellitus on alveolar bone loss after 30 days of ligature-induced periodontal disease. Sixty-four Wistar rats were randomly distributed into four experimental groups. Diabetes was induced in Groups II and IV, while periodontal disease was induced in Groups III and IV; Group I was used as control. In order to perform the radiographic assessment of the specimens, the rats were killed on the 3rd and 30th days of the study. Radiographic measurements were assessed with ANOVA and Tukey's test to determine statistically significant differences (p < 0.05). It was observed that Groups III and IV featured greater bone loss when compared to Groups I and II. Only the diabetic group with periodontal disease (Group IV) featured statistically significant greater bone loss when compared to the other groups. These results suggested that the alveolar bone loss resulting from the periodontal disease installation is greater when associated to the diabetes mellitus.en
dc.format.extent188-192
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/19431958
dc.identifier.citationJournal of the International Academy of Periodontology, v. 11, n. 2, p. 188-192, 2009.
dc.identifier.issn1466-2094
dc.identifier.lattes3373230215078349
dc.identifier.lattes2640929291808415
dc.identifier.scopus2-s2.0-67149112238
dc.identifier.urihttp://hdl.handle.net/11449/70980
dc.language.isoeng
dc.relation.ispartofJournal of the International Academy of Periodontology
dc.relation.ispartofsjr0,397
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectstreptozocin
dc.subjectanimal
dc.subjectblood
dc.subjectcephalometry
dc.subjectcomparative study
dc.subjectexperimental diabetes mellitus
dc.subjectinstrumentation
dc.subjectligation
dc.subjectmale
dc.subjectosteolysis
dc.subjectperiodontal disease
dc.subjectradiography
dc.subjectrandomization
dc.subjectrat
dc.subjecttime
dc.subjecttooth radiography
dc.subjectWistar rat
dc.subjectAlveolar Bone Loss
dc.subjectAnimals
dc.subjectCephalometry
dc.subjectDiabetes Mellitus, Experimental
dc.subjectFurcation Defects
dc.subjectLigation
dc.subjectMale
dc.subjectPeriodontal Diseases
dc.subjectRadiography, Dental, Digital
dc.subjectRandom Allocation
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectStreptozocin
dc.subjectTime Factors
dc.titleEffect of induced diabetes mellitus on alveolar bone loss after 30 days of ligature-induced periodontal diseaseen
dc.typeArtigo
unesp.author.lattes3373230215078349[6]
unesp.author.lattes2640929291808415
unesp.author.orcid0000-0003-2376-1024[2]
unesp.author.orcid0000-0001-8498-8199[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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Artigos - Fisiologia e Patologia - FOAR
Artigos - Diagnóstico e Cirurgia - FOAR