Maternal care of the whole litter improves the success rate of diabetes in pregnancy in rats

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dc.contributor.authorFloriano, Juliana Ferreira [UNESP]
dc.contributor.authorBarbosa, Angélica Mércia Pascon [UNESP]
dc.contributor.authorde Oliveira, Rafael Guilen [UNESP]
dc.contributor.authorVega, Sofía [UNESP]
dc.contributor.authorCatinelli, Bruna Bologna [UNESP]
dc.contributor.authorGarcia, Gabriela Azevedo [UNESP]
dc.contributor.authorReyes, David Rafael [UNESP]
dc.contributor.authorSobrevia, Luis [UNESP]
dc.contributor.authorRudge, Marilza Vieira Cunha [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionImperial College London
dc.contributor.institutionPontificia Universidad Católica de Chile
dc.contributor.institutionUniversidad de Sevilla
dc.contributor.institutionUniversity of Queensland
dc.contributor.institutionSchool of Medicine and Health Sciences
dc.date.accessioned2023-07-29T15:13:35Z
dc.date.available2023-07-29T15:13:35Z
dc.date.issued2022-12-01
dc.description.abstractInduction of diabetes mellitus by streptozotocin (STZ) in rats at birth is of high mortality and low success rate when male puppies are separated from females, prioritizing females breastfeeding. Cross-parental care of the entire litter and SZT-induced diabetes up to 12 h post-birth become with high success rate, low animal death, and females with glycaemia >140 mg/dL on the 90 postnatal day. Cross-parental care is more effective in STZ-induction of diabetes, which is maintained during pregnancy (diabetes in pregnancy), than the conventional protocol of male separation at birth.en
dc.description.affiliationSão Paulo State University (UNESP) Botucatu Medical School, Botucatu
dc.description.affiliationNational Heart and Lung Institute Imperial College London
dc.description.affiliationCellular and Molecular Physiology Laboratory (CMPL) Department of Obstetrics Division of Obstetrics and Gynaecology School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile
dc.description.affiliationDepartment of Physiology Faculty of Pharmacy Universidad de Sevilla
dc.description.affiliationUniversity of Queensland Centre for Clinical Research (UQCCR) Faculty of Medicine and Biomedical Sciences University of Queensland
dc.description.affiliationTecnologico de Monterrey Eutra The Institute for Obesity Research School of Medicine and Health Sciences, Nuevo León
dc.description.affiliationSão Paulo State University (UNESP) School of Philosophy and Sciences, Marília
dc.description.affiliationUnespSão Paulo State University (UNESP) Botucatu Medical School, Botucatu
dc.description.affiliationUnespSão Paulo State University (UNESP) School of Philosophy and Sciences, Marília
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipUniversidade Estadual Paulista
dc.description.sponsorshipIdFAPESP: 2016/01743–5
dc.description.sponsorshipIdFAPESP: 2017/21783–4
dc.format.extent42-45
dc.identifierhttp://dx.doi.org/10.1016/j.placenta.2022.11.002
dc.identifier.citationPlacenta, v. 130, p. 42-45.
dc.identifier.doi10.1016/j.placenta.2022.11.002
dc.identifier.issn1532-3102
dc.identifier.issn0143-4004
dc.identifier.scopus2-s2.0-85141488213
dc.identifier.urihttp://hdl.handle.net/11449/249347
dc.language.isoeng
dc.relation.ispartofPlacenta
dc.sourceScopus
dc.titleMaternal care of the whole litter improves the success rate of diabetes in pregnancy in ratsen
dc.typeArtigo
unesp.author.orcid0000-0001-5802-2243 0000-0001-5802-2243 0000-0001-5802-2243 0000-0001-5802-2243 0000-0001-5802-2243[8]

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