Effects of malathion and cadmium on acetylcholinesterase activity and metallothionein levels in the fish Seriola dumerilli

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dc.contributor.authorJebali, J.
dc.contributor.authorBanni, M.
dc.contributor.authorGuerbej, H.
dc.contributor.authorAlmeida, E. A.
dc.contributor.authorBannaoui, A.
dc.contributor.authorBoussetta, H.
dc.contributor.institutionEcole Super Hort & Elevage
dc.contributor.institutionINSTM
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Ibn Izhour
dc.date.accessioned2014-05-20T14:03:01Z
dc.date.available2014-05-20T14:03:01Z
dc.date.issued2006-03-01
dc.description.abstractThe potential use of acetylcholinesterase (AChE) and metallothionein (MT) responses as biomarker of organophosphorous (OPs) and trace metal were assessed in fish Seriola dumerilli exposed to 0, 4, 6 mg/kg of malathion for 2, 7 and 13 days, and to 0, 50, 100, 250 mu g/kg of Cd for 2 days. Brain AChE was significantly inhibited after 2 and 7 days of malathion exposure, in a dose-response manner, but no inhibition was observed after 13 days of exposure. When exposed to Cd for 2 days, S. dumerelli presented an increase in AChE activity at a concentration of 50 mu g/kg, but a strong and dose-dependent AChE inhibition at 100 and 250 mu g/kg. Cd treatment also caused a rapid increase in MTs concentration in liver, even at the lower concentration. Our experiments indicate that the measurement of hepatic MT concentration and brain AChE activity in S. dumerilli would be useful biomarkers of OP and Cd exposure and/or effects.en
dc.description.affiliationEcole Super Hort & Elevage, Lab Biochim & Toxicol Environm, Chott Mariem 4042, Tunisia
dc.description.affiliationINSTM, Ctr Monastir, Monastir, Tunisia
dc.description.affiliationUNESP, IBILCE, Dept Quim & Ciências Ambientais, BR-15054000 Sao Jose do Rio Preto, SP, Brazil
dc.description.affiliationUniv Ibn Izhour, Fac Sci, Lab Eau & Environm, Agadir, Morocco
dc.description.affiliationUnespUNESP, IBILCE, Dept Quim & Ciências Ambientais, BR-15054000 Sao Jose do Rio Preto, SP, Brazil
dc.format.extent93-98
dc.identifierhttp://dx.doi.org/10.1007/s10695-006-0041-2
dc.identifier.citationFish Physiology and Biochemistry. Dordrecht: Springer, v. 32, n. 1, p. 93-98, 2006.
dc.identifier.doi10.1007/s10695-006-0041-2
dc.identifier.issn0920-1742
dc.identifier.lattes6713400866382255
dc.identifier.urihttp://hdl.handle.net/11449/22209
dc.identifier.wosWOS:000240057700012
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofFish Physiology and Biochemistry
dc.relation.ispartofjcr1.735
dc.relation.ispartofsjr0,690
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectacetylcholinesterasept
dc.subjectbiomarkerspt
dc.subjectcadmiumpt
dc.subjectmalathionpt
dc.subjectmetallothioneinpt
dc.subjectmetalspt
dc.subjectorganophosphorouspt
dc.subjectSeriola dumerillipt
dc.titleEffects of malathion and cadmium on acetylcholinesterase activity and metallothionein levels in the fish Seriola dumerillien
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer
unesp.author.lattes6713400866382255
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Pretopt

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Artigos - Química e Ciências Ambientais - IBILCE