Vaccine immune response and interference of colostral antibodies in calves vaccinated against rabies at 2, 4 and 6 months of age born from antirabies revaccinated females

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dc.contributor.authorFilho, O. A. [UNESP]
dc.contributor.authorMegid, Jane [UNESP]
dc.contributor.authorGeronutti, L. [UNESP]
dc.contributor.authorRatti, J.
dc.contributor.authorAlmeida, M. F. A.
dc.contributor.authorKataoka, A. P. A. G.
dc.contributor.authorMartorelli, L. F. A.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionZoonosis Control Ctr
dc.date.accessioned2014-05-20T13:39:59Z
dc.date.available2014-05-20T13:39:59Z
dc.date.issued2012-06-01
dc.description.abstractConsidering the high prevalence of rabies in cattle, we aimed to evaluate the interference of colostral antibodies transferred to calves after birth and the benefit of administering an antirabies vaccination in two-month-old calves compared to vaccinating at 4 and 6 months of age. Calves born from females revaccinated against rabies during the third trimester of pregnancy were studied. Forty-eight hours after parturition, blood samples from dams and offspring were collected, and antirabies neutralizing antibody titers were analyzed using the Rapid Focus Fluorescent Inhibition Test. We found that all calves had similar titers of antibodies transferred through the colostrum. Furthermore, none of the calves presented a satisfactory serological response after the first vaccination, but all had an appropriate response after revaccination. This study demonstrates that antirabies vaccination should be recommended for calves at two months of age in endemic and epizootic situations. (C) 2011 Elsevier Ltd. All rights reserved.en
dc.description.affiliationUNESP, Sch Vet Med & Anim Sci, Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
dc.description.affiliationZoonosis Control Ctr, Rabies Lab, São Paulo, Brazil
dc.description.affiliationUnespUNESP, Sch Vet Med & Anim Sci, Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent396-400
dc.identifierhttp://dx.doi.org/10.1016/j.rvsc.2011.03.025
dc.identifier.citationResearch In Veterinary Science. Oxford: Elsevier B.V., v. 92, n. 3, p. 396-400, 2012.
dc.identifier.doi10.1016/j.rvsc.2011.03.025
dc.identifier.issn0034-5288
dc.identifier.urihttp://hdl.handle.net/11449/13891
dc.identifier.wosWOS:000302985000009
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofResearch in Veterinary Science
dc.relation.ispartofjcr1.616
dc.relation.ispartofsjr0,593
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectRabiesen
dc.subjectVaccinationen
dc.subjectColostral antibodiesen
dc.subjectHumoral immune responseen
dc.subjectCattleen
dc.subjectCalvesen
dc.titleVaccine immune response and interference of colostral antibodies in calves vaccinated against rabies at 2, 4 and 6 months of age born from antirabies revaccinated femalesen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.orcid0000-0002-6540-7157[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt

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