In vivo evaluation of the biocompatibility of three current bonding agents

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dc.contributor.authorTeixeira, H. M.
dc.contributor.authorDo Nascimento, ABL
dc.contributor.authorHebling, J.
dc.contributor.authorCosta, CAD
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCaruaru Sch Dent
dc.contributor.institutionUniv Pernambuco
dc.date.accessioned2014-02-26T17:25:11Z
dc.date.accessioned2014-05-20T13:44:43Z
dc.date.available2014-02-26T17:25:11Z
dc.date.available2014-05-20T13:44:43Z
dc.date.issued2006-07-01
dc.description.abstractThe aim of this in vivo study was to evaluate the biocompatibility of three current bonding agents and calcium hydroxide cement. Sixty polyethylene tubes filled with the following materials: Group 1: Prime & Bond NT (PB - Dentsply, US; Group 2: Bond 1 (BO - Jeneric/Pentron, US); Group 3: Optibond Solo (OP - Kerr, US); and Group 4 (control): calcium hydroxide cement - Dycal (CH - Dentsply, US) were implanted into the connective tissue of 30 rats. After 15, 30 and 60 days, the implants were excised and the animals sacrificed. The biopsies were immersed in Karnovsky (pH, 7.2) fixative solution for 48 hours, and processed using routine histological technique. Six-micron-thick sections were cut and stained with hematoxilin and eosin and Masson's trichome technique. Microscopic evaluation was used to compare the connective tissue reactions caused by the experimental and control materials adjacent to the tube opening. At 15 days, the experimental and control materials triggered a moderate to intense inflammatory response which gave rise to a thick capsule adjacent to the tube opening. With time, the inflammatory reaction decreased. At 60 days, the connective tissue adjacent to the bonding agents exhibited a persistent inflammatory response mediated by macrophages and giant cells which were engulfing displaced resin components. on the other hand, for the control group (calcium hydroxide) no inflammatory response associated with a thin capsule adjacent to the material was observed even at the 30-day period. The hard-setting calcium hydroxide cement allowed complete healing and was considered more biocompatible than the bonding agents.en
dc.description.affiliationUniv São Paulo State, Araraquara Sch Dent, UNESP, Dept Physiol & Pathol, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationCaruaru Sch Dent, Dept Operat Dent, Caruaru, PE, Brazil
dc.description.affiliationUniv Pernambuco, Sch Dent, Dept Restorat Dent, Camaragibe, PE, Brazil
dc.description.affiliationUniv São Paulo State, Araraquara Sch Dent, UNESP, Dept Orthodont & Pediat Dent, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationUnespUniv São Paulo State, Araraquara Sch Dent, UNESP, Dept Physiol & Pathol, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationUnespUniv São Paulo State, Araraquara Sch Dent, UNESP, Dept Orthodont & Pediat Dent, BR-14801903 Araraquara, SP, Brazil
dc.format.extent542-550
dc.identifierhttp://dx.doi.org/10.1111/j.1365-2842.2005.01591.x
dc.identifier.citationJournal of Oral Rehabilitation. Oxford: Blackwell Publishing, v. 33, n. 7, p. 542-550, 2006.
dc.identifier.doi10.1111/j.1365-2842.2005.01591.x
dc.identifier.issn0305-182X
dc.identifier.urihttp://hdl.handle.net/11449/15684
dc.identifier.wosWOS:000238064800011
dc.language.isoeng
dc.publisherBlackwell Publishing
dc.relation.ispartofJournal of Oral Rehabilitation
dc.relation.ispartofjcr2.051
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectbiocompatibilitypt
dc.subjectbonding agentpt
dc.subjectconnective healingpt
dc.subjectcalcium hydroxidept
dc.titleIn vivo evaluation of the biocompatibility of three current bonding agentsen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderBlackwell Publishing
unesp.author.orcid0000-0002-7455-6867[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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