Temperature effects on baroreflex control of heart rate in the toad, Rhinella schneideri

Página do item simplificado
dc.contributor.authorZena, Lucas A. [UNESP]
dc.contributor.authorGargaglioni, Luciane H. [UNESP]
dc.contributor.authorBícego, Kênia Cardoso [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-08-06T16:13:55Z
dc.date.available2015-08-06T16:13:55Z
dc.date.issued2015
dc.description.abstractFor an adequate blood supply to support metabolic demands, vertebrates regulate blood pressure to maintain sufficient perfusion to avoid ischemia and other tissue damage like edema. Using a pharmacological approach (phenylephrine and sodium nitroprusside) we investigated baroreflex sensitivity at 15, 25, and 30 °C in toads Rhinella schneideri. Baroreflex sensitivity presented a high thermal dependence (Q10 = 1.9–4.1), and the HR– baroreflex curve was shifted up and to the right as temperature increased from 15 to 30 °C. Baroreflex variables, namely, HR range, gain50 (maximal gain) and normalized gain50 increased 206, 235, and 160% from 15 to 30 °C, respectively. The cardiac limb of the baroreflex response to pharmacological treatments was significantly blunted after full autonomic blockade. In addition, there was a clear baroreflex–HR response mainly to hypotension at all three temperatures tested. These findings indicate that toads present temperature dependence for cardiac limb of the barostatic response and the cardiac baroreflex response in R. schneideri is primarily hypotensive rather than hypertensive as well as crocodilians and mammals. Thus, the cardiac baroreflex compensation to changes in arterial pressure might present different patterns among amphibian species, since the previously reported bradycardic compensation to hypertension in some anurans was not observed in the toad used in the present study.en
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Ciências Agrárias e Veterinárias de Jaboticabal, Jaboticabal, Via de acesso Prof. Paulo D Castellane, Rural, CEP 14884-900, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Ciências Agrárias e Veterinárias de Jaboticabal, Jaboticabal, Via de acesso Prof. Paulo D Castellane, Rural, CEP 14884-900, SP, Brasil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdFAPESP: 2008/57712-4
dc.description.sponsorshipIdFAPESP: 2012/17379-0
dc.format.extent81-88
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S1095643314002025
dc.identifier.citationComparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, v. 179, p. 81-88, 2015.
dc.identifier.doi10.1016/j.cbpa.2014.09.027
dc.identifier.issn1095-6433
dc.identifier.lattes5850453468994497
dc.identifier.lattes0169967378071426
dc.identifier.orcid0000-0003-1810-5313[3]
dc.identifier.urihttp://hdl.handle.net/11449/126091
dc.language.isoeng
dc.relation.ispartofComparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
dc.relation.ispartofjcr2.258
dc.relation.ispartofsjr0,836
dc.rights.accessRightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectBaroreflex sensitivityen
dc.subjectAmphibiansen
dc.subjectBlood pressureen
dc.subjectSodium nitroprussideen
dc.subjectPhenylephrineen
dc.titleTemperature effects on baroreflex control of heart rate in the toad, Rhinella schneiderien
dc.typeArtigo
unesp.author.lattes5850453468994497
unesp.author.lattes0169967378071426
unesp.author.orcid0000-0003-1810-5313[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt
unesp.departmentMorfologia e Fisiologia Animalpt

Arquivos

Coleções

Artigos - Morfologia e Fisiologia Animal - FCAV