IMPROVING CONTROL STRATEGIES OF INFECTIONS BY RESISTANT PATHOGENS IN a HOSPITAL NETWORK

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dc.contributor.authorVilches, Thomas Nogueira
dc.contributor.authorAlmeida, Gabriel Berg de [UNESP]
dc.contributor.authorFortaleza, Carlos Magno Castelo Branco [UNESP]
dc.contributor.authorFerreira, Claudia Pio [UNESP]
dc.contributor.institutionYork Univ
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T12:00:27Z
dc.date.available2023-07-29T12:00:27Z
dc.date.issued2023-05-06
dc.description.abstractThe efficacy of infection prevention and control on several hospital networks is assessed. We tested two kinds of strategy, a network-topology-based allocation and a R-0-based allocation, where R0 is the basic reproduction number of the infection. For this, a multi-patch deterministic model simulates the spread of carbapenemase-producing Enterobacteriaceae in several theoretical hospital networks parametrized by data from Brazil. Our results show that: (i) the allocation methods based on the R-0 of the hospitals may work better than the network-topology-based allocations; (ii) results from control efficacy for a specific hospital network cannot be generalized to other types of networks. Putting together the global network topology with local factors that drive pathogens transmission, the R-0-based allocation method seems to be enough to control of healthcare-associated infections. Overall, the obtained results emphasize the importance of data collection on infection transmission and patient transfers.en
dc.description.affiliationYork Univ, Agent Based Modelling Lab, 4700 Keele St, Toronto, ON M3J 1P3, Canada
dc.description.affiliationSao Paulo State Univ, Med Sch, Dept Trop Dis, Botucatu, SP, Brazil
dc.description.affiliationSao Paulo State Univ, Inst Biosci, Biostat Dept, Botucatu, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Med Sch, Dept Trop Dis, Botucatu, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Inst Biosci, Biostat Dept, Botucatu, SP, Brazil
dc.format.extent17
dc.identifierhttp://dx.doi.org/10.1142/S0218339023500262
dc.identifier.citationJournal of Biological Systems. Singapore: World Scientific Publ Co Pte Ltd, 17 p., 2023.
dc.identifier.doi10.1142/S0218339023500262
dc.identifier.issn0218-3390
dc.identifier.urihttp://hdl.handle.net/11449/245628
dc.identifier.wosWOS:000984830800001
dc.language.isoeng
dc.publisherWorld Scientific Publ Co Pte Ltd
dc.relation.ispartofJournal Of Biological Systems
dc.sourceWeb of Science
dc.subjectOrdinary Differential Equations
dc.subjectMathematical Epidemiology
dc.subjectHealthcare Acquired Infections
dc.titleIMPROVING CONTROL STRATEGIES OF INFECTIONS BY RESISTANT PATHOGENS IN a HOSPITAL NETWORKen
dc.typeArtigo
dcterms.rightsHolderWorld Scientific Publ Co Pte Ltd

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