Physically modified bacterial cellulose biocomposites for guided tissue regeneration

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dc.contributor.authorde Olyveira, Gabriel Molina [UNESP]
dc.contributor.authordos Santos, Márcio Luiz [UNESP]
dc.contributor.authorRiccardi, Carla dos Santos [UNESP]
dc.contributor.authorCosta, Ligia Maria Manzine
dc.contributor.authorDaltro, Paula Braga [UNESP]
dc.contributor.authorBasmaji, Pierre
dc.contributor.authorDaltro, Gildásio de Cerqueira
dc.contributor.authorGuastaldi, Antônio Carlos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do ABC (UFABC)
dc.contributor.institutionInnovatec's-Biotechnology Research and Development
dc.contributor.institutionUniversidade Federal da Bahia (UFBA)
dc.date.accessioned2018-12-11T17:25:11Z
dc.date.available2018-12-11T17:25:11Z
dc.date.issued2015-01-01
dc.description.abstractBacterial cellulose (BC) has become established as a remarkably versatile biomaterial and can be used in a wide variety of scientific applications, especially for medical devices. In this work, the bacterial cellulose fermentation process was modified by the addition of chondroitin sulfate to the culture medium before the bacteria was inoculated. Besides, the potential of gamma irradiation treatment for the modification of the BC surface properties, in enhancing its potential for biomedical applications, was also analyzed. For guided tissue regeneration purposes, biomimetic precipitation of calcium phosphate of biological interest from simulated body fluid on bacterial cellulose was studied. The influence of chondroitin sulfate on bacterial cellulose was analyzed by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and thermogravimetric analysis (TGA), as well as after CaP coatings produced by a biomimetic route. FTIR analysis showed interaction between bacterial cellulose nanobiocomposites and calcium phosphate. XRD demonstrated formation of amorphous calcium phosphate and sodium chloride on bacterial cellulose nanobiocomposites. SEM images proved faster calcium phosphate deposition in non-irradiated samples. The different samples showed significant variation in thermal properties.en
dc.description.affiliationDepartment of Physical Chemistry-UNESP
dc.description.affiliationDepartment of Nanoscience and Advanced Materials-UFABC
dc.description.affiliationInnovatec's-Biotechnology Research and Development
dc.description.affiliationCollege Hospital Complex (COM-HUPES); UFBA
dc.description.affiliationUnespDepartment of Physical Chemistry-UNESP
dc.format.extent1657-1664
dc.identifierhttp://dx.doi.org/10.1166/sam.2015.2283
dc.identifier.citationScience of Advanced Materials, v. 7, n. 8, p. 1657-1664, 2015.
dc.identifier.doi10.1166/sam.2015.2283
dc.identifier.issn1947-2943
dc.identifier.issn1947-2935
dc.identifier.scopus2-s2.0-84931863631
dc.identifier.urihttp://hdl.handle.net/11449/177383
dc.language.isoeng
dc.relation.ispartofScience of Advanced Materials
dc.relation.ispartofsjr0,322
dc.relation.ispartofsjr0,322
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBacterial cellulose
dc.subjectDental materials
dc.subjectNanocomposites
dc.subjectNanoskin®
dc.subjectScaffolds
dc.titlePhysically modified bacterial cellulose biocomposites for guided tissue regenerationen
dc.typeArtigo
unesp.author.lattes6443430122330366[8]
unesp.author.lattes0173401604473200[3]
unesp.author.orcid0000-0002-6433-3555[8]
unesp.author.orcid0000-0003-2192-5312[3]

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