Experimental paracoccidioidomycosis

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dc.contributor.authorCoelho, Kunie Iabuki Rabello [UNESP]
dc.contributor.authorDefaveri, Julio [UNESP]
dc.contributor.authorRezkallah-Iwasso, Maria Thereza [UNESP]
dc.contributor.authorPeraçoli, Maria Terezinha S. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2019-10-06T16:22:46Z
dc.date.available2019-10-06T16:22:46Z
dc.date.issued2018-01-01
dc.description.abstractParacoccidioidomycosis seems to be primarily a disease of man, in whom it runs a variable course and often with prolonged periods of incubation. Hamsters were introduced as experimental animals for the study of paracoccidioidomycosis by Guimaraes, who inoculated the fungus by the testicular route and was able to reproduce lesions similar to those of the progressive human disease. The mouse is the species most often utilized in experimental research in paracoccidioidomycosis. The intraperitoneal route has been widely used in the study of paracoccidioidomycosis in isogenic mice. Calich et al. have published a large body of information related to host factors that influence the outcome of the disease in mice. Guinea pigs were the animals most frequently used for the study of experimental paracoccidioidomycosis up to the early 1970s and were, also, the first animal species in which the experimental infection proved successful.en
dc.description.affiliationDepartment of Pathology Botucatu Medical School University of the State of São Paulo (UNESP)
dc.description.affiliationDepartment of Microbiology and Immunology Institute of Biosciences University of the State of São Paulo (UNESP)
dc.description.affiliationUnespDepartment of Pathology Botucatu Medical School University of the State of São Paulo (UNESP)
dc.description.affiliationUnespDepartment of Microbiology and Immunology Institute of Biosciences University of the State of São Paulo (UNESP)
dc.format.extent87-107
dc.identifierhttp://dx.doi.org/10.1201/9781351075329
dc.identifier.citationParacoccidioidomycosis, p. 87-107.
dc.identifier.doi10.1201/9781351075329
dc.identifier.scopus2-s2.0-85063516014
dc.identifier.urihttp://hdl.handle.net/11449/188898
dc.language.isoeng
dc.relation.ispartofParacoccidioidomycosis
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.titleExperimental paracoccidioidomycosisen
dc.typeCapítulo de livro

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Artigos - Patologia - FMB
Artigos - Microbiologia e Imunologia - IBB