Espécies reativas de oxigênio no controle neurovegetativo da pressão arterial

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dc.contributor.authorCardoso, Leonardo M.
dc.contributor.authorColombari, Débora S. A. [UNESP]
dc.contributor.authorMenani, José Vanderlei [UNESP]
dc.contributor.authorDe Paula, Patrícia M. [UNESP]
dc.contributor.authorChianca Jr., Deoclécio A.
dc.contributor.authorColombari, Eduardo [UNESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Ouro Preto (UFOP)
dc.date.accessioned2014-05-27T11:21:48Z
dc.date.available2014-05-27T11:21:48Z
dc.date.issued2006-01-01
dc.description.abstractThe control of the blood pressure depends on the activity of select groups of neurons present in the central nervous system. Evidence has demonstrated that the redox state (a balance between oxidizing and reducing species) is involved in the control of neuronal activity, which suggests that the redox state can influence the neuronal transmission within the central nervous system acting on the neuronal modulation of biological functions. For instance, the glutamatergic transmission may be widely affected by reactive oxygen species, oxidizing agents that have been extensively investigated due to their involvement in physiological and pathological processes. In the present article, we discuss the main experimental finds that support the hypothesis that reactive oxygen species have important role in physiological (and pathological) modulation of the cardiovascular function through alterations in the sympathetic and parasympathetic system. Therefore, reactive oxygen species can actively participate in the development of cardiovascular diseases like hypertension when the balance in the redox state is disrupted.en
dc.description.affiliationDepartamento de Farmacologia Escola Paulista de Medicina UNIFESP, São Paulo- SP
dc.description.affiliationDepartamento de Fisiologia e Patologia Faculdade de Odontologia de Araraquara UNESP
dc.description.affiliationDepartamento de Ciências Biológicas Universidade Federal de Ouro Preto UFOP
dc.description.affiliationDepartamentos de Fisiologia Escola Paulista de Medicina UNIFESP, São Paulo- SP
dc.description.affiliationDepartamento de Fisiologia Escola Paulista de Medicina UNIFESP, Rua Botucatu, 862, CEP 04023-060, São Paulo- SP
dc.description.affiliationUnespDepartamento de Fisiologia e Patologia Faculdade de Odontologia de Araraquara UNESP
dc.format.extent77-88
dc.identifierhttp://www.revistas.usp.br/rmrp/article/view/366
dc.identifier.citationMedicina, v. 39, n. 1, p. 77-88, 2006.
dc.identifier.file2-s2.0-33750341048.pdf
dc.identifier.issn0076-6046
dc.identifier.lattes1023597870118105
dc.identifier.lattes4544450092427426
dc.identifier.lattes0201361251312074
dc.identifier.scopus2-s2.0-33750341048
dc.identifier.urihttp://hdl.handle.net/11449/68757
dc.language.isopor
dc.relation.ispartofMedicina
dc.relation.ispartofsjr0,125
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCardiovascular Regulation
dc.subjectGlutamate
dc.subjectHydrogen Peroxide
dc.subjectReactive Oxygen Species
dc.subjectneurotransmitter
dc.subjectreactive oxygen metabolite
dc.subjectarterial pressure
dc.subjectautonomic nervous system
dc.subjectblood pressure regulation
dc.subjectcardiovascular system
dc.subjectcentral nervous system
dc.subjectcholinergic system
dc.subjectconference paper
dc.titleEspécies reativas de oxigênio no controle neurovegetativo da pressão arterialpt
dc.title.alternativeReactive oxygen species in the autonomic control of the blood pressureen
dc.typeTrabalho apresentado em evento
dcterms.licensehttp://www.revistas.usp.br/rmrp/about/editorialPolicies#openAccessPolicy
unesp.author.lattes1023597870118105
unesp.author.lattes4544450092427426[6]
unesp.author.lattes0201361251312074[4]
unesp.author.orcid0000-0002-1395-4036[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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