Epidemiology of inflammatory bowel diseases in the state of Rio Grande do Sul, Brazil

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dc.contributor.authorCassol, Ornella Sari
dc.contributor.authorZabot, Gilmara Pandolfo
dc.contributor.authorSaad-Hossne, Rogerio [UNESP]
dc.contributor.authorPadoin, Alexandre
dc.contributor.institutionIMED Medical School
dc.contributor.institutionPontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
dc.contributor.institutionColoprocto Canoas Clinic
dc.contributor.institutionHospital Moinhos de Vento (HMV)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T14:03:24Z
dc.date.available2023-07-29T14:03:24Z
dc.date.issued2022-08-14
dc.description.abstractBACKGROUND This is the first study on the epidemiology of inflammatory bowel diseases (IBDs) in Rio Grande do Sul (RS), the southernmost state of Brazil with the country’s fifth largest population. Crohn’s disease (CD) and ulcerative colitis (UC) are collectively termed IBDs. They have high incidence and prevalence rates in high-income countries, although in recent years there has been a change in the classic geographical distribution of IBDs, with growing rates in traditionally low-incidence regions. AIM To estimate the incidence and prevalence of IBDs in the RS state, Brazil, between 2014 and 2019. METHODS This is a cross-sectional descriptive observational study. Patients with IBD who had initiated treatment and met the inclusion criteria of the RS state free drug distribution program were included. Data were obtained from registration or renewal records of the RS state specialty pharmacy. The male, female, and total populations were estimated according to mid-year data from the Brazilian Institute of Geography and Statistics, which served as a reference for calculating the incidence and prevalence rates of IBDs during the study period. Results were described using mean, standard deviation, and range. RESULTS We included 1082 patients with IBD, of whom 57.5% were female and 42.5% were male. Patients with CD accounted for 72.45% of the sample, and those with UC accounted for 27.54%. IBD prevalence during the study period was 9.51 per 100000 population, of which 6.89 corresponded to people with CD and 2.62, to people with UC. Incidence rates per 100000 population/year were 2.54 in 2014, 2.61 in 2015, 1.91 in 2016, 0.80 in 2017, 0.83 in 2018, and 0.96 in 2019. The mean IBD incidence rate per 100000 population was 1.61, of which 1.17 corresponded to CD and 0.44, to UC. The mean age was 41 years, and patients were mostly aged 30-40 years. Prevalence by region was higher in the state capital metropolitan area: 12.69 per 100000 population. CONCLUSION Our results demonstrated an IBD prevalence of 9.51% and incidence of 1.61 per 100000 population. The patients were predominantly female, and CD was more prevalent than UC.en
dc.description.affiliationDepartment of Coloproctology IMED Medical School, RS
dc.description.affiliationGraduate Program in Medicine and Health Sciences Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), RS
dc.description.affiliationDepartment of Coloproctology Coloprocto Canoas Clinic, RS
dc.description.affiliationDepartment of Coloproctology Hospital Moinhos de Vento (HMV), RS
dc.description.affiliationDepartment of Surgery and Orthopaedics Universidade Estadual Paulista (UNESP), SP
dc.description.affiliationUnespDepartment of Surgery and Orthopaedics Universidade Estadual Paulista (UNESP), SP
dc.format.extent4174-4181
dc.identifierhttp://dx.doi.org/10.3748/wjg.v28.i30.4174
dc.identifier.citationWorld Journal of Gastroenterology, v. 28, n. 30, p. 4174-4181, 2022.
dc.identifier.doi10.3748/wjg.v28.i30.4174
dc.identifier.issn2219-2840
dc.identifier.issn1007-9327
dc.identifier.scopus2-s2.0-85137732201
dc.identifier.urihttp://hdl.handle.net/11449/249138
dc.language.isoeng
dc.relation.ispartofWorld Journal of Gastroenterology
dc.sourceScopus
dc.subjectCrohn’s disease
dc.subjectEpidemiology
dc.subjectIncidence
dc.subjectInflammatory bowel diseases
dc.subjectPrevalence
dc.subjectUlcerative colitis
dc.titleEpidemiology of inflammatory bowel diseases in the state of Rio Grande do Sul, Brazilen
dc.typeArtigo
unesp.author.orcid0000-0003-0867-6593 0000-0003-0867-6593[1]
unesp.author.orcid0000-0002-1253-4945 0000-0002-1253-4945[2]
unesp.author.orcid0000-0002-8166-0304[3]
unesp.author.orcid0000-0002-9754-4818[4]

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