Low-level laser therapy on the treatment of oral and cutaneous pemphigus vulgaris: case report

dc.contributor.authorMinicucci, Eliana Maria [UNESP]
dc.contributor.authorMiot, Hélio Amante [UNESP]
dc.contributor.authorCatharino Sartori Barraviera, Silvia Regina [UNESP]
dc.contributor.authorAlmeida-Lopes, Luciana
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionNUPEN Res & Educ Ctr Photo Therapy Hlth Sci
dc.date.accessioned2014-05-20T13:34:06Z
dc.date.available2014-05-20T13:34:06Z
dc.date.issued2012-09-01
dc.description.abstractPemphigus vulgaris is a chronic autoimmune mucocutaneous disease that initially is manifested by painful intraoral erosions and ulcers which spread to other mucosa and the skin, generally more than 5 months after oral lesion manifestation. The treatment consists of prednisone alone or in combination with an immunosuppressive agent, and the clinical response is perceived within 2 to 4 weeks. Low-level laser therapy has been effective in accelerating the healing of injured tissue, thus inducing cell proliferation and increasing ATP, nucleic acid, and collagen synthesis. We reported two cases of pemphigus vulgaris that received systemic treatment associated with low-level laser therapy for oral and cutaneous lesions. We observed prompt analgesic effect in oral lesions and accelerated healing of oral and cutaneous wounds. Therefore, the present report suggests LLLT as a noninvasive technique that should be considered as an adjuvant therapy in oral and skin disorders in patients with PV.en
dc.description.affiliationSão Paulo State Univ UNESP, Dept Dermatol & Radiotherapy, Botucatu Sch Med, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationNUPEN Res & Educ Ctr Photo Therapy Hlth Sci, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNESP, Dept Dermatol & Radiotherapy, Botucatu Sch Med, BR-18618000 Botucatu, SP, Brazil
dc.format.extent1103-1106
dc.identifierhttp://dx.doi.org/10.1007/s10103-012-1101-8
dc.identifier.citationLasers In Medical Science. London: Springer London Ltd, v. 27, n. 5, p. 1103-1106, 2012.
dc.identifier.doi10.1007/s10103-012-1101-8
dc.identifier.issn0268-8921
dc.identifier.lattes2543633050941005
dc.identifier.urihttp://hdl.handle.net/11449/11677
dc.identifier.wosWOS:000307406500031
dc.language.isoeng
dc.publisherSpringer London Ltd
dc.relation.ispartofLasers in Medical Science
dc.relation.ispartofjcr1.949
dc.relation.ispartofsjr0,713
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectLow-level laser therapyen
dc.subjectPemphigusen
dc.subjectWound healingen
dc.titleLow-level laser therapy on the treatment of oral and cutaneous pemphigus vulgaris: case reporten
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer London Ltd
unesp.author.lattes2543633050941005
unesp.author.orcid0000-0002-2596-9294[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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