Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia

Página do item simplificado
dc.contributor.authorMinicucci, E. M.
dc.contributor.authorLopes, L. F.
dc.contributor.authorCrocci, A. J.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2014-05-20T15:25:38Z
dc.date.available2014-05-20T15:25:38Z
dc.date.issued2003-01-01
dc.description.abstractThe frequency of dental abnormalities, such as delayed dental development, microdontia, hypoplasia, agenesis, V-shaped root and shortened root was evaluated in 76 acute lymphoblastic leukemia (ALL) pediatric patients who had been off chemotherapy for 6 months. These children had been subjected to one of the three Brazilian Protocols or the BFM86 Protocol. The patients were divided into three groups: Group I (GI; high risk) treated with one of the three Brazilian Protocols who received high-dose chemotherapy, intensive maintenance and cranial radiotherapy; Group II (GII; low risk) who were also treated with one of the three Brazilian Protocols using low-intensive chemotherapy with no radiotherapy; and Group III (GIII) based on the BFM86 Protocol.Of 76 children, 13 showed no dental abnormalities (8 were at the age of tooth formation). The remaining 63 children (82.9%) showed at least one dental anomaly.The abnormalities were probably caused by the type, intensity, frequency of the treatment and age of the patients at ALL diagnosis and this might have important consequences for the children's dental development. (C) 2002 Elsevier B.V. Ltd. All rights reserved.en
dc.description.affiliationSão Paulo State Univ, Sch Med Botucatu, Dept Pathol, São Paulo, Brazil
dc.description.affiliationCanc Hosp, Dept Pediat, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Biosci Inst Botucatu, Dept Stat, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Sch Med Botucatu, Dept Pathol, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Biosci Inst Botucatu, Dept Stat, São Paulo, Brazil
dc.format.extent45-50
dc.identifierhttp://dx.doi.org/10.1016/S0145-2126(02)00080-2
dc.identifier.citationLeukemia Research. Oxford: Pergamon-Elsevier B.V., v. 27, n. 1, p. 45-50, 2003.
dc.identifier.doi10.1016/S0145-2126(02)00080-2
dc.identifier.issn0145-2126
dc.identifier.urihttp://hdl.handle.net/11449/36008
dc.identifier.wosWOS:000180568700007
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofLeukemia Research
dc.relation.ispartofjcr2.319
dc.relation.ispartofsjr1,063
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectodontogenesis drugs effectspt
dc.subjectantineoplastic agents adverse effectspt
dc.subjectchemotherapy dental abnormalitiespt
dc.subjectlate effects of ALL treatmentpt
dc.titleDental abnormalities in children after chemotherapy treatment for acute lymphoid leukemiaen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

Arquivos

Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Patologia - FMB