On a possible dual role for central noradrenaline in the control of hydromineral fluid intake

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dc.contributor.authorDe-Luca, L. A. [UNESP]
dc.contributor.authorCamargo, L. A. A. [UNESP]
dc.contributor.authorMenani, José Vanderlei [UNESP]
dc.contributor.authorRenzi, Antonio [UNESP]
dc.contributor.authorSaad, W. A. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:17:56Z
dc.date.available2014-05-27T11:17:56Z
dc.date.issued1994-01-01
dc.description.abstractNoradrenaline (NOR) is a neurotransmitter presenl in the central nervous system which is related to the control of ingestive behavior of food and fluids. We describe here the relationship between NOR and intake of water and NaCl solution, fluids that are essential for a normal body fluid electrolytic balance. Central NOR has an inhibitory effect on fluid intake, but it either induces or not alterations in food intake. Several ways of inducing water intake, such as water deprivation, meal-associated water intake, administration of angiotensinergic, cholinergic or beta-adrenergic agonists, or administration of hyperosmotic solutions, are inhibited by alpha-adrenergic agonists. Need-induced sodium intake by sodium-depleted animals is also inhibited by alpha-adrenergic agonists. NOR can also facilitate fluid intake. Water intake is elicited by NOR and the integrity of central noradrenergic systems is necessary for a normal expression of water or salt intake in dehydrated animals. The angiotensinergic component of either behavior apparently depends on a central noradrenergic system. NOR probably facililates fluid intake by acting on postsynaptic receptors, but we do not know how it inhibits fluid infake. The inhibitory and facilitatory effects of NOR on ingestive behavior suggest a dual role for this neurotransmitter in the control of hydromineral fluid intake.en
dc.description.affiliationDepto. de Ciencias Fisiologicas Faculdade de Odontologia UNESP, 14801-903 Araraquara
dc.description.affiliationUnespDepto. de Ciencias Fisiologicas Faculdade de Odontologia UNESP, 14801-903 Araraquara
dc.format.extent905-914
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso
dc.identifier.citationBrazilian Journal of Medical and Biological Research, v. 27, n. 4, p. 905-914, 1994.
dc.identifier.issn0100-879X
dc.identifier.lattes1023597870118105
dc.identifier.lattes6551236936295697
dc.identifier.scopus2-s2.0-0028327454
dc.identifier.urihttp://hdl.handle.net/11449/64461
dc.identifier.wosWOS:A1994NE41500007
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.relation.ispartofjcr1.492
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectingestive behavior
dc.subjectnoradrenaline
dc.subjectsodium intake
dc.subjectwater intake
dc.subjectalpha adrenergic receptor
dc.subjectangiotensin
dc.subjectcarbachol
dc.subjectclonidine
dc.subjectidazoxan
dc.subjectnoradrenalin
dc.subjectoxidopamine
dc.subjectphenylephrine
dc.subjectprazosin
dc.subjectyohimbine
dc.subjectanimal experiment
dc.subjectcentral nervous system
dc.subjectfluid intake
dc.subjectfood intake
dc.subjectintracerebroventricular drug administration
dc.subjectneurotransmission
dc.subjectnonhuman
dc.subjectosmosis
dc.subjectrat
dc.subjectreview
dc.subjectwater deprivation
dc.subjectAdrenergic alpha-Agonists
dc.subjectAngiotensin II
dc.subjectAnimal
dc.subjectDrinking
dc.subjectEating
dc.subjectNorepinephrine
dc.subjectRats
dc.subjectReceptors, Adrenergic, alpha
dc.subjectSupport, Non-U.S. Gov't
dc.titleOn a possible dual role for central noradrenaline in the control of hydromineral fluid intakeen
dc.typeResenha
dcterms.licensehttp://www.scielo.br/revistas/bjmbr/iaboutj.htm#Copyright
unesp.author.lattes1023597870118105
unesp.author.lattes6551236936295697
unesp.author.orcid0000-0001-8270-2652[1]
unesp.author.orcid0000-0003-1167-4441[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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