Effects of physical training on serum and pituitary growth hormone contents in diabetic rats

Página do item simplificado
dc.contributor.authorCuriacos de Almeida Leme, Jose Alexandre [UNESP]
dc.contributor.authorde Araujo, Michel Barbosa [UNESP]
dc.contributor.authorde Moura, Leandro Pereira [UNESP]
dc.contributor.authorGomes, Ricardo Jose [UNESP]
dc.contributor.authorde Moura, Rodrigo Ferreira [UNESP]
dc.contributor.authorRogatto, Gustavo Puggina [UNESP]
dc.contributor.authorRostom de Mello, Maria Alice [UNESP]
dc.contributor.authorLuciano, Eliete [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:49:08Z
dc.date.accessioned2014-05-20T13:58:41Z
dc.date.available2013-09-30T18:49:08Z
dc.date.available2014-05-20T13:58:41Z
dc.date.issued2009-12-01
dc.description.abstractThe present study investigated the effects of moderate physical training on some of the parameters in the GH-IGF axis in experimental diabetic rats. Male Wistar rats were allocated into the following groups: sedentary control, trained control, sedentary diabetic, trained diabetic. Diabetes was induced by alloxan (32 mg/kg, b.w. iv). The physical training protocol consisted of 1 h swimming session/day, 5 days/week for 8 weeks supporting a load corresponding to 90% of maximal lactate steady state. After the experimental period, blood was collected to measure serum glucose, insulin, triglycerides, albumin, insulin-like growth factors-I (IGF-I), and growth hormone (GH). Pituitary gland was removed for GH quantification. Diabetes increased blood glucose and triglycerides and decreased insulin, IGF-I, serum and pituitary GH. Physical training decreased glucose and triglycerides, and also counteracted the reduction of serum IGF-I in diabetic rats. In conclusion, physical training recovered serum IGF-I showing no alteration of serum or pituitary GH levels.en
dc.description.affiliationSão Paulo State Univ UNESP, Dept Phys Educ, BR-13506900 São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNESP, Dept Phys Educ, BR-13506900 São Paulo, Brazil
dc.format.extent304-308
dc.identifierhttp://dx.doi.org/10.1007/s11102-009-0178-y
dc.identifier.citationPituitary. New York: Springer, v. 12, n. 4, p. 304-308, 2009.
dc.identifier.doi10.1007/s11102-009-0178-y
dc.identifier.issn1386-341X
dc.identifier.lattes2933779830637191
dc.identifier.urihttp://hdl.handle.net/11449/20852
dc.identifier.wosWOS:000270977600004
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofPituitary
dc.relation.ispartofjcr2.730
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectPituitaryen
dc.subjectPhysical trainingen
dc.subjectDiabetesen
dc.subjectGrowth hormone and IGFen
dc.titleEffects of physical training on serum and pituitary growth hormone contents in diabetic ratsen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer
unesp.author.lattes2933779830637191
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Rio Claropt
Arquivos
Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Coleções
Artigos - Educação Física - IBRC