Effects of physical training on serum and pituitary growth hormone contents in diabetic rats
dc.contributor.author | Curiacos de Almeida Leme, Jose Alexandre [UNESP] | |
dc.contributor.author | de Araujo, Michel Barbosa [UNESP] | |
dc.contributor.author | de Moura, Leandro Pereira [UNESP] | |
dc.contributor.author | Gomes, Ricardo Jose [UNESP] | |
dc.contributor.author | de Moura, Rodrigo Ferreira [UNESP] | |
dc.contributor.author | Rogatto, Gustavo Puggina [UNESP] | |
dc.contributor.author | Rostom de Mello, Maria Alice [UNESP] | |
dc.contributor.author | Luciano, Eliete [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2013-09-30T18:49:08Z | |
dc.date.accessioned | 2014-05-20T13:58:41Z | |
dc.date.available | 2013-09-30T18:49:08Z | |
dc.date.available | 2014-05-20T13:58:41Z | |
dc.date.issued | 2009-12-01 | |
dc.description.abstract | The present study investigated the effects of moderate physical training on some of the parameters in the GH-IGF axis in experimental diabetic rats. Male Wistar rats were allocated into the following groups: sedentary control, trained control, sedentary diabetic, trained diabetic. Diabetes was induced by alloxan (32 mg/kg, b.w. iv). The physical training protocol consisted of 1 h swimming session/day, 5 days/week for 8 weeks supporting a load corresponding to 90% of maximal lactate steady state. After the experimental period, blood was collected to measure serum glucose, insulin, triglycerides, albumin, insulin-like growth factors-I (IGF-I), and growth hormone (GH). Pituitary gland was removed for GH quantification. Diabetes increased blood glucose and triglycerides and decreased insulin, IGF-I, serum and pituitary GH. Physical training decreased glucose and triglycerides, and also counteracted the reduction of serum IGF-I in diabetic rats. In conclusion, physical training recovered serum IGF-I showing no alteration of serum or pituitary GH levels. | en |
dc.description.affiliation | São Paulo State Univ UNESP, Dept Phys Educ, BR-13506900 São Paulo, Brazil | |
dc.description.affiliationUnesp | São Paulo State Univ UNESP, Dept Phys Educ, BR-13506900 São Paulo, Brazil | |
dc.format.extent | 304-308 | |
dc.identifier | http://dx.doi.org/10.1007/s11102-009-0178-y | |
dc.identifier.citation | Pituitary. New York: Springer, v. 12, n. 4, p. 304-308, 2009. | |
dc.identifier.doi | 10.1007/s11102-009-0178-y | |
dc.identifier.issn | 1386-341X | |
dc.identifier.lattes | 2933779830637191 | |
dc.identifier.uri | http://hdl.handle.net/11449/20852 | |
dc.identifier.wos | WOS:000270977600004 | |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.relation.ispartof | Pituitary | |
dc.relation.ispartofjcr | 2.730 | |
dc.rights.accessRights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | Pituitary | en |
dc.subject | Physical training | en |
dc.subject | Diabetes | en |
dc.subject | Growth hormone and IGF | en |
dc.title | Effects of physical training on serum and pituitary growth hormone contents in diabetic rats | en |
dc.type | Artigo | |
dcterms.license | http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0 | |
dcterms.rightsHolder | Springer | |
unesp.author.lattes | 2933779830637191 | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Biociências, Rio Claro | pt |
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