Current advances in nanocarriers for biomedical research and their applications

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dc.contributor.authorRout, George Kerry
dc.contributor.authorShin, Han-Seung
dc.contributor.authorGouda, Sushanto
dc.contributor.authorSahoo, Sabuj
dc.contributor.authorDas, Gitishree
dc.contributor.authorFraceto, Leonardo Fernandes [UNESP]
dc.contributor.authorPatra, Jayanta Kumar
dc.contributor.institutionUtkal Univesity
dc.contributor.institutionDongguk University
dc.contributor.institutionAmity University
dc.contributor.institutionDongguk University-Seoul
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2019-10-06T16:51:01Z
dc.date.available2019-10-06T16:51:01Z
dc.date.issued2018-11-05
dc.description.abstractNanodrug delivery systems sometimes referred to as nanocarriers (NCs) are nanoengineered biocompatible materials or devices, which in conjugation with desired bioactive compounds plays an indispensable functional role in the field of pharmaceutical and allied sciences. The diversified ability of this bioengineered colloidal or noncolloidal molecule to breach the biological barriers to reach the targeted location in the biological system uplifts its other versatile natures of mono- or polydispersity in biodistribution. Furthermore, its nontoxicity and biodegradability result in making it a unique candidate for its purpose as drug delivery system. A number of different conjugations of chemical and biological substances are currently implemented for the synthesis of this biofunctional hybrid nanomaterial by simple methods. The use of these bioconjugated as a nanoparticulated system is currently being used for the treatment of various deadly incurable infectious diseases such as tuberculosis and disorders such as diabetes and cancers of various forms. Henceforth, the objective of the present review article is to provide overviews of the diversified and types of nanoparticulated systems, their beneficial as well as deleterious impacts along with the future prospect of nanodrug delivery system based on present status.en
dc.description.affiliationP.G. Department of Biotechnology Utkal Univesity
dc.description.affiliationDepartment of Food Science and Biotechnology Dongguk University
dc.description.affiliationAmity Institute of Forestry and Wildlife Amity University
dc.description.affiliationResearch Institute of Biotechnology & Medical Converged Science Dongguk University-Seoul
dc.description.affiliationSão Paulo State University (UNESP) Institute of Science and Technology of Sorocaba
dc.description.affiliationUnespSão Paulo State University (UNESP) Institute of Science and Technology of Sorocaba
dc.format.extent1053-1062
dc.identifierhttp://dx.doi.org/10.1080/21691401.2018.1478843
dc.identifier.citationArtificial Cells, Nanomedicine and Biotechnology, v. 46, n. sup2, p. 1053-1062, 2018.
dc.identifier.doi10.1080/21691401.2018.1478843
dc.identifier.issn2169-141X
dc.identifier.issn2169-1401
dc.identifier.scopus2-s2.0-85053668155
dc.identifier.urihttp://hdl.handle.net/11449/189752
dc.language.isoeng
dc.relation.ispartofArtificial Cells, Nanomedicine and Biotechnology
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectbiocompatible
dc.subjectbiodistribution
dc.subjectdrug delivery
dc.subjectNanocarriers
dc.subjectnanoparticles
dc.titleCurrent advances in nanocarriers for biomedical research and their applicationsen
dc.typeResenha
unesp.author.orcid0000-0003-4118-4355[7]

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