Evidence of natural Zika virus infection in neotropical non-human primates in Brazil
dc.contributor.author | Terzian, Ana Carolina B. | |
dc.contributor.author | Zini, Nathalia | |
dc.contributor.author | Sacchetto, Lívia | |
dc.contributor.author | Rocha, Rebeca Froes | |
dc.contributor.author | Parra, Maisa Carla Pereira | |
dc.contributor.author | Del Sarto, Juliana Lemos | |
dc.contributor.author | Dias, Ana Carolina Fialho | |
dc.contributor.author | Coutinho, Felipe | |
dc.contributor.author | Rayra, Jéssica | |
dc.contributor.author | da Silva, Rafael Alves | |
dc.contributor.author | Costa, Vivian Vasconcelos | |
dc.contributor.author | Fernandes, Natália Coelho Couto De Azevedo | |
dc.contributor.author | Réssio, Rodrigo | |
dc.contributor.author | Díaz-Delgado, Josué | |
dc.contributor.author | Guerra, Juliana | |
dc.contributor.author | Cunha, Mariana S. | |
dc.contributor.author | Catão-Dias, José Luiz | |
dc.contributor.author | Bittar, Cintia [UNESP] | |
dc.contributor.author | Reis, Andréia Francesli Negri | |
dc.contributor.author | Santos, Izalco Nuremberg Penha dos | |
dc.contributor.author | Ferreira, Andréia Cristina Marascalchi | |
dc.contributor.author | Cruz, Lilian Elisa Arão Antônio | |
dc.contributor.author | Rahal, Paula [UNESP] | |
dc.contributor.author | Ullmann, Leila [UNESP] | |
dc.contributor.author | Malossi, Camila [UNESP] | |
dc.contributor.author | Araújo Jr, João Pessoa de [UNESP] | |
dc.contributor.author | Widen, Steven | |
dc.contributor.author | de Rezende, Izabela Maurício | |
dc.contributor.author | Mello, Érica | |
dc.contributor.author | Pacca, Carolina Colombelli | |
dc.contributor.author | Kroon, Erna Geessien | |
dc.contributor.author | Trindade, Giliane | |
dc.contributor.author | Drumond, Betânia | |
dc.contributor.author | Chiaravalloti-Neto, Francisco | |
dc.contributor.author | Vasilakis, Nikos | |
dc.contributor.author | Teixeira, Mauro M. | |
dc.contributor.author | Nogueira, Maurício Lacerda | |
dc.contributor.institution | CEP: 15090-000 | |
dc.contributor.institution | Universidade Federal de Minas Gerais (UFMG) | |
dc.contributor.institution | Pacaembú | |
dc.contributor.institution | Universidade de São Paulo (USP) | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.contributor.institution | Vila Sinibaldi | |
dc.contributor.institution | 301 University Blvd | |
dc.contributor.institution | São Bernardo | |
dc.contributor.institution | Jardim Francisco Fernandes | |
dc.date.accessioned | 2019-10-06T16:02:52Z | |
dc.date.available | 2019-10-06T16:02:52Z | |
dc.date.issued | 2018-12-01 | |
dc.description.abstract | In Africa, Old World Primates are involved in the maintenance of sylvatic circulation of ZIKV. However, in Brazil, the hosts for the sylvatic cycle remain unknown. We hypothesized that free-living NHPs might play a role in urban/periurban ZIKV dynamics, thus we undertook an NHP ZIKV investigation in two cities in Brazil. We identified ZIKV-positive NHPs and sequences obtained were phylogenetically related to the American lineage of ZIKV. Additionally, we inoculated four C. penicillata with ZIKV and our results demonstrated that marmosets had a sustained viremia. The natural and experimental infection of NHPs with ZIKV, support the hypothesis that NHPs may be a vertebrate host in the maintainance of ZIKV transmission/circulation in urban tropical settings. Further studies are needed to understand the role they may play in maintaining the urban cycle of the ZIKV and how they may be a conduit in establishing an enzootic transmission cycle in tropical Latin America. | en |
dc.description.affiliation | São José do Rio Preto School of Medicine (FAMERP) Avenida Brigadeiro Faria Lima 5416 CEP: 15090-000, Vila São Pedro | |
dc.description.affiliation | Laboratório de Vírus - Universidade Federal de Minas Gerais (UFMG) Avenida Antônio Carlos 6627 CEP: 31270-901 Pampulha | |
dc.description.affiliation | Center for Drug Research and Development Instituto de Ciências Biológicas Universidade Federal de Minas Gerais (UFMG) Avenida Antônio Carlos 6627 CEP: 31270-901 Pampulha | |
dc.description.affiliation | Instituto Adolfo Lutz (IAL) Avenida Dr. Arnaldo 351 − 7 Andar Sala 706 CEP: 01246-000 Pacaembú | |
dc.description.affiliation | Laboratory of Wildlife Comparative Pathology Department of Pathology School of Veterinary Medicine and Animal Sciences University of São Paulo (LAPOCM-FMVZ-USP) Avenida Orlando Marques de Paiva 87 CEP: 05508-270 | |
dc.description.affiliation | Department of Biology Institute of Biosciences Letters and Exact Sciences – São Paulo State University São José do Rio Preto – (IBILCE/UNESP), Rua Cristóvão Colombo, 2265, CEP: 15054-000 | |
dc.description.affiliation | Epidemiological Surveillance Departament of São José do Rio Preto Avenida Romeu Strazzi 199 CEP: 15084-010 Vila Sinibaldi | |
dc.description.affiliation | São Paulo State University (Unesp) Institute for Biotechnology Alameda das Tecomarias s/n CEP: 18607-440 Chácara Capão Bonito | |
dc.description.affiliation | Department of Biochemistry and Molecular Biology University of Texas Medical Branch 301 University Blvd | |
dc.description.affiliation | Centro de Controle de Zoonoses Belo Horizonte Council Rua Édna Quintel 173 CEP: 31270-705 São Bernardo | |
dc.description.affiliation | Faceres Medical School Avenida Anísio Haddad 6751 CEP: 15090-305 Jardim Francisco Fernandes | |
dc.description.affiliation | Department of Epidemiology School of Public Health of the University of São Paulo Avenida Dr. Arnaldo 715 CEP: 01246-904 | |
dc.description.affiliation | Department of Pathology and Center of Biodefense and Emerging Infectious Diseases Center for Tropical Diseases Institute for Human Infections and Immunity University of Texas Medical Branch 301 University Blvd | |
dc.description.affiliationUnesp | Department of Biology Institute of Biosciences Letters and Exact Sciences – São Paulo State University São José do Rio Preto – (IBILCE/UNESP), Rua Cristóvão Colombo, 2265, CEP: 15054-000 | |
dc.description.affiliationUnesp | São Paulo State University (Unesp) Institute for Biotechnology Alameda das Tecomarias s/n CEP: 18607-440 Chácara Capão Bonito | |
dc.description.sponsorship | National Institutes of Health | |
dc.description.sponsorshipId | National Institutes of Health: R24AI120942 | |
dc.identifier | http://dx.doi.org/10.1038/s41598-018-34423-6 | |
dc.identifier.citation | Scientific Reports, v. 8, n. 1, 2018. | |
dc.identifier.doi | 10.1038/s41598-018-34423-6 | |
dc.identifier.issn | 2045-2322 | |
dc.identifier.lattes | 7991082362671212 | |
dc.identifier.orcid | 0000-0001-5693-6148 | |
dc.identifier.scopus | 2-s2.0-85055615937 | |
dc.identifier.uri | http://hdl.handle.net/11449/188275 | |
dc.language.iso | eng | |
dc.relation.ispartof | Scientific Reports | |
dc.rights.accessRights | Acesso aberto | |
dc.source | Scopus | |
dc.title | Evidence of natural Zika virus infection in neotropical non-human primates in Brazil | en |
dc.type | Artigo | |
unesp.author.lattes | 7991082362671212[23] | |
unesp.author.orcid | 0000-0003-2999-3395[17] | |
unesp.author.orcid | 0000-0002-2048-4589[18] | |
unesp.author.orcid | 0000-0003-2686-8740[34] | |
unesp.author.orcid | 0000-0003-1102-2419[37] | |
unesp.author.orcid | 0000-0001-5693-6148[23] |