Microbiological assay for lomefloxacin in coated tablets

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dc.contributor.authorGomes, Greici Cristiani [UNESP]
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T08:47:28Z
dc.date.available2022-04-29T08:47:28Z
dc.date.issued2006-01-01
dc.description.abstractThe validation of a microbiological assay, applying cylinder plate method for determination of the activity of lomefloxacin in coated tablets is described. Using a strain of Bacillus subtilis ATCC 9372 as the test organism, lomefloxacin was measured in concentrations ranging from 2.0 to 8.0 μg/mL. The method validation showed that it is linear (r= 0.9999), precise (relative standard deviation = 1.15%), and accurate (it measured the added quantities). The excipients did not interfere in the determination. It was concluded that the microbiological assay is satisfactory for quantitation of lomefloxacin in tablets.en
dc.description.affiliationUniversidade Estadual Paulista (UNESP) Faculdade de Ciências Farmacêuticas UNESP, Rod. Araraquara-Jaú, km 1, CEP 14801-902, Araraquara, SP
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP) Faculdade de Ciências Farmacêuticas UNESP, Rod. Araraquara-Jaú, km 1, CEP 14801-902, Araraquara, SP
dc.format.extent1077-1079
dc.identifierhttp://dx.doi.org/10.1093/jaoac/89.4.1077
dc.identifier.citationJournal of AOAC International, v. 89, n. 4, p. 1077-1079, 2006.
dc.identifier.doi10.1093/jaoac/89.4.1077
dc.identifier.issn1060-3271
dc.identifier.scopus2-s2.0-33750694271
dc.identifier.urihttp://hdl.handle.net/11449/231800
dc.language.isoeng
dc.relation.ispartofJournal of AOAC International
dc.sourceScopus
dc.titleMicrobiological assay for lomefloxacin in coated tabletsen
dc.typeArtigo

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