Titanium-Based Alloy Surface Modification with TiO2and Poly(sodium 4-styrenesulfonate) Multilayers for Dental Implants

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dc.contributor.authorKitagawa, Igor L. [UNESP]
dc.contributor.authorMiyazaki, Celina M.
dc.contributor.authorPitol-Palin, Letícia [UNESP]
dc.contributor.authorOkamoto, Roberta [UNESP]
dc.contributor.authorDe Vasconcellos, Luana M. R. [UNESP]
dc.contributor.authorConstantino, Carlos J. L. [UNESP]
dc.contributor.authorLisboa-Filho, Paulo N. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionIFSP Federal Institute of Education
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.date.accessioned2021-06-25T10:57:05Z
dc.date.available2021-06-25T10:57:05Z
dc.date.issued2021-01-01
dc.description.abstractImplant placement is an important repair method in dentistry and orthopedics. Increasing efforts have focused on optimizing the biocompatibility and osseointegration properties of titanium (Ti) and Ti-based alloys. In this work, Ti-based alloys were modified by the layer-by-layer (LbL) technique, which is a simple and versatile method for surface modification. The morphology and chemical structure of LbL films of poly(sodium 4-styrenesulfonate) (PSS) and Ti dioxide (TiO2) nanoparticles were first characterized employing ultraviolet-visible and Fourier-transform infrared spectroscopies as well as atomic force microscopy for further application in Ti-based alloy implants. The changes provoked by the LbL PSS/TiO2 film on the Ti-based alloy surfaces were then investigated by scanning electron microscopy and micro-Raman techniques. Finally, in vivo tests (immunolabeling and biomechanical analysis) performed with screw implants in rats suggested that PSS/TiO2 multilayers promote changes in both topography and chemical surface properties of the screw, providing beneficial effects for osteoblast activity. This simple and relatively low-cost growth process can open up possibilities to improve dental implants and, probably, bone implants in general.en
dc.description.affiliationSchool of Sciences Department of Physics UNESP São Paulo State University
dc.description.affiliationScience and Technology of São Paulo IFSP Federal Institute of Education Campus Birigui
dc.description.affiliationCCTS Federal University of São Carlos
dc.description.affiliationAraçatuba Dental School Department of Basic Science UNESP São Paulo State University
dc.description.affiliationInstitute of Science and Technology Department of Biosciences and Oral Diagnosis UNESP São Paulo State University
dc.description.affiliationSchool of Technology and Applied Sciences Department of Physics UNESP São Paulo State University
dc.description.affiliationUnespSchool of Sciences Department of Physics UNESP São Paulo State University
dc.description.affiliationUnespAraçatuba Dental School Department of Basic Science UNESP São Paulo State University
dc.description.affiliationUnespInstitute of Science and Technology Department of Biosciences and Oral Diagnosis UNESP São Paulo State University
dc.description.affiliationUnespSchool of Technology and Applied Sciences Department of Physics UNESP São Paulo State University
dc.identifierhttp://dx.doi.org/10.1021/acsabm.0c01348
dc.identifier.citationACS Applied Bio Materials.
dc.identifier.doi10.1021/acsabm.0c01348
dc.identifier.issn2576-6422
dc.identifier.scopus2-s2.0-85103504240
dc.identifier.urihttp://hdl.handle.net/11449/207548
dc.language.isoeng
dc.relation.ispartofACS Applied Bio Materials
dc.sourceScopus
dc.subjectdental implant
dc.subjectin vivo tests
dc.subjectlayer-by-layer
dc.subjectPSS
dc.subjectTiO2
dc.titleTitanium-Based Alloy Surface Modification with TiO2and Poly(sodium 4-styrenesulfonate) Multilayers for Dental Implantsen
dc.typeArtigo
unesp.author.orcid0000-0003-2583-3001[2]
unesp.author.orcid0000-0002-7734-4069[7]

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