Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats
dc.contributor.author | Mulinari-santos, Gabriel [UNESP] | |
dc.contributor.author | Santos, Jaqueline Silva Dos [UNESP] | |
dc.contributor.author | Palin, Letícia Pitol [UNESP] | |
dc.contributor.author | Silva, Ana Cláudia Ervolino Da [UNESP] | |
dc.contributor.author | Antoniali, Cristina [UNESP] | |
dc.contributor.author | Faverani, Leonardo Perez [UNESP] | |
dc.contributor.author | Okamoto, Roberta [UNESP] | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2021-07-14T10:49:57Z | |
dc.date.available | 2021-07-14T10:49:57Z | |
dc.date.issued | 2019-10-07 | |
dc.description.abstract | Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduction in active periodontitis. Therefore, losartan is suggested to be effective in bone formation stages, as well as in the synthesis of matrix proteins and mineralization. | en |
dc.description.affiliation | Universidade Estadual Paulista, Faculdade de Odontologia de Araçatuba | |
dc.description.affiliation | Universidade Estadual Paulista, Faculdade de odontologia de Araçatuba | |
dc.description.affiliationUnesp | Universidade Estadual Paulista, Faculdade de Odontologia de Araçatuba | |
dc.description.affiliationUnesp | Universidade Estadual Paulista, Faculdade de odontologia de Araçatuba | |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
dc.description.sponsorshipId | FAPESP: 2016/03245-2; 2017/23082-3; 2017/16912-0 | |
dc.format.extent | - | |
dc.identifier | http://dx.doi.org/10.1590/1678-7757-2018-0574 | |
dc.identifier.citation | Journal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 27, p. -, 2019. | |
dc.identifier.doi | 10.1590/1678-7757-2018-0574 | |
dc.identifier.file | S1678-77572019000100479.pdf | |
dc.identifier.issn | 1678-7757 | |
dc.identifier.issn | 1678-7765 | |
dc.identifier.scielo | S1678-77572019000100479 | |
dc.identifier.uri | http://hdl.handle.net/11449/213095 | |
dc.language.iso | eng | |
dc.publisher | Faculdade De Odontologia De Bauru - USP | |
dc.relation.ispartof | Journal of Applied Oral Science | |
dc.rights.accessRights | Acesso aberto | |
dc.source | SciELO | |
dc.subject | Losartan | en |
dc.subject | Spontaneously hypertensive rats | en |
dc.subject | Bone | en |
dc.subject | Hypertension | en |
dc.title | Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats | en |
dc.type | Artigo | |
unesp.author.orcid | 0000-0003-4489-6868[1] |
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