Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats

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dc.contributor.authorMulinari-santos, Gabriel [UNESP]
dc.contributor.authorSantos, Jaqueline Silva Dos [UNESP]
dc.contributor.authorPalin, Letícia Pitol [UNESP]
dc.contributor.authorSilva, Ana Cláudia Ervolino Da [UNESP]
dc.contributor.authorAntoniali, Cristina [UNESP]
dc.contributor.authorFaverani, Leonardo Perez [UNESP]
dc.contributor.authorOkamoto, Roberta [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-07-14T10:49:57Z
dc.date.available2021-07-14T10:49:57Z
dc.date.issued2019-10-07
dc.description.abstractHypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduction in active periodontitis. Therefore, losartan is suggested to be effective in bone formation stages, as well as in the synthesis of matrix proteins and mineralization.en
dc.description.affiliationUniversidade Estadual Paulista, Faculdade de Odontologia de Araçatuba
dc.description.affiliationUniversidade Estadual Paulista, Faculdade de odontologia de Araçatuba
dc.description.affiliationUnespUniversidade Estadual Paulista, Faculdade de Odontologia de Araçatuba
dc.description.affiliationUnespUniversidade Estadual Paulista, Faculdade de odontologia de Araçatuba
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2016/03245-2; 2017/23082-3; 2017/16912-0
dc.format.extent-
dc.identifierhttp://dx.doi.org/10.1590/1678-7757-2018-0574
dc.identifier.citationJournal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 27, p. -, 2019.
dc.identifier.doi10.1590/1678-7757-2018-0574
dc.identifier.fileS1678-77572019000100479.pdf
dc.identifier.issn1678-7757
dc.identifier.issn1678-7765
dc.identifier.scieloS1678-77572019000100479
dc.identifier.urihttp://hdl.handle.net/11449/213095
dc.language.isoeng
dc.publisherFaculdade De Odontologia De Bauru - USP
dc.relation.ispartofJournal of Applied Oral Science
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectLosartanen
dc.subjectSpontaneously hypertensive ratsen
dc.subjectBoneen
dc.subjectHypertensionen
dc.titleLosartan improves alveolar bone dynamics in normotensive rats but not in hypertensive ratsen
dc.typeArtigo
unesp.author.orcid0000-0003-4489-6868[1]

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