Bioactive pyrones and flavonoids from Cryptocarya ashersoniana seedlings

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dc.contributor.authorRicardo, Maria A. G. [UNESP]
dc.contributor.authorAndreo, Márcio A. [UNESP]
dc.contributor.authorCavalheiro, Alberto J. [UNESP]
dc.contributor.authorGamboa, Ian C. [UNESP]
dc.contributor.authorBolzani, Vanderlan S. [UNESP]
dc.contributor.authorSilva, Dulce H. S. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T08:47:48Z
dc.date.available2022-04-29T08:47:48Z
dc.date.issued2004-09-19
dc.description.abstractThe bioassay directed fractionation of the EtOH extract from leaves of Cryptocarya ashersoniana seedlings led to the isolation of two flavonol glucosides: iso-quercitrin and hyperin, which exhibited free radical scavenging activity towards DPPH (IC50 34.4 μM and 32.7 μM, respectively) and were compared to standard compounds rutin (IC50 27.0 μM) and catechin (IC50 41.4 μM). Investigation of extracts from the seedlings roots and stems afforded one antifungal styrylpyrone: goniothalamine, and two dihydropyrones: 6-propyl-5,6-dihydro-2-pyrone and the new 6-[(4′-ethyl-9′-oxabicyclo[3.3.1]non-6′-en-3′-yl)methyl] -5,6-dihydro-2H-pyran-2-one, which had its structure determined by detailed analysis of MS and NMR data, including 2D experiments.en
dc.description.affiliationInstituto de Química Universidade Estadual Paulista, CP. 359, Araraquara, CEP 14800-900, São Paulo, SP
dc.description.affiliationUnespInstituto de Química Universidade Estadual Paulista, CP. 359, Araraquara, CEP 14800-900, São Paulo, SP
dc.format.extent127-136
dc.identifier.citationArkivoc, v. 2004, n. 6, p. 127-136, 2004.
dc.identifier.issn1424-6376
dc.identifier.scopus2-s2.0-5444274519
dc.identifier.urihttp://hdl.handle.net/11449/231850
dc.language.isoeng
dc.relation.ispartofArkivoc
dc.sourceScopus
dc.subjectAntioxidant
dc.subjectCryptocarya ashersoniana
dc.subjectDPPH
dc.subjectFlavonoid
dc.subjectFree radical scavenger
dc.subjectLauraceae
dc.subjectPyrone
dc.titleBioactive pyrones and flavonoids from Cryptocarya ashersoniana seedlingsen
dc.typeArtigo

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