PHENYLBUTANOID AND TAXANE-LIKE METABOLITES FROM NEEDLES OF TAXUS-BREVIFOLIA
dc.contributor.author | Chu, A. | |
dc.contributor.author | Furlan, Maysa [UNESP] | |
dc.contributor.author | Davin, L. B. | |
dc.contributor.author | Zajicek, J. | |
dc.contributor.author | Towers, GHN | |
dc.contributor.author | Soucybreau, C. M. | |
dc.contributor.author | Rettig, S. J. | |
dc.contributor.author | Croteau, R. | |
dc.contributor.author | Lewis, N. G. | |
dc.contributor.institution | WASHINGTON STATE UNIV | |
dc.contributor.institution | UNIV BRITISH COLUMBIA | |
dc.contributor.institution | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-20T15:23:48Z | |
dc.date.available | 2014-05-20T15:23:48Z | |
dc.date.issued | 1994-07-01 | |
dc.description.abstract | The structures for brevifoliol and three baccatin VI derivatives were revised to possess the novel 11(15 --> 1)-abeotaxane tricylic skeleton based on X-ray crystallographic studies. Four more new rearranged taxane derivatives related to brevifoliol and the unusual phenylbutanoid, (-)-rhododendrol, were isolated from the needles of Taxus breuifolia. Their structures were established as 10 beta-benzoxy-5 alpha-(3'-dimethylamino-3'-phenyl)-propanoxy-1 beta-hydroxy- 7 beta,9 alpha,13 alpha-triacetoxy-11(15 --> 1)-abeotaxa-4(20),11-diene; 10 beta-benzoxy-1 beta-hydroxy-5 alpha-(3'-methylamino-3'-phenyl)- propanoxy-7 beta,9 alpha,l3 alpha-triacetoxy-11(15 --> 1)-abeotaxa-4(20),11-diene; 10 beta-benzoxy-5 alpha-cinnamoxy-1 beta-hydroxy-7 beta,9 alpha,13 alpha-triacetoxy-1 1(15 --> 1)-abeotaxa-4(20),11-diene; 10 beta-benzoxy-1 beta,5 alpha-dihydroxy-7 beta,9 alpha,13 alpha-triacetoxy-11(15 --> 1)-abeotaxa-4(20),11-diene and 2(R)-hydroxy-4-(4'-hydroxyphenyl)-butane. | en |
dc.description.affiliation | WASHINGTON STATE UNIV,INST BIOL CHEM,PULLMAN,WA 99164 | |
dc.description.affiliation | WASHINGTON STATE UNIV,NMR SPECT CTR,PULLMAN,WA 99164 | |
dc.description.affiliation | UNIV BRITISH COLUMBIA,DEPT BOT,VANCOUVER V6T 2Z1,BC,CANADA | |
dc.description.affiliation | UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 2Z1,BC,CANADA | |
dc.description.affiliation | UNIV ESTADUAL PAULISTA,INST QUIM,BR-14800900 ARARAQUARA,SP,BRAZIL | |
dc.description.affiliationUnesp | UNIV ESTADUAL PAULISTA,INST QUIM,BR-14800900 ARARAQUARA,SP,BRAZIL | |
dc.format.extent | 975-985 | |
dc.identifier | http://dx.doi.org/10.1016/S0031-9422(00)90475-8 | |
dc.identifier.citation | Phytochemistry. Oxford: Pergamon-Elsevier B.V., v. 36, n. 4, p. 975-985, 1994. | |
dc.identifier.doi | 10.1016/S0031-9422(00)90475-8 | |
dc.identifier.issn | 0031-9422 | |
dc.identifier.lattes | 1308042794786872 | |
dc.identifier.uri | http://hdl.handle.net/11449/34506 | |
dc.identifier.wos | WOS:A1994NY14400032 | |
dc.language.iso | eng | |
dc.publisher | Elsevier B.V. | |
dc.relation.ispartof | Phytochemistry | |
dc.relation.ispartofjcr | 3.186 | |
dc.relation.ispartofsjr | 1,048 | |
dc.rights.accessRights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | TAXUS BREVIFOLIA | pt |
dc.subject | TAXACEAE | pt |
dc.subject | YEW | pt |
dc.subject | NEEDLES | pt |
dc.subject | CRYSTAL STRUCTURE | pt |
dc.subject | TAXOL | pt |
dc.subject | DITERPENOIDS | pt |
dc.subject | TAXANES | pt |
dc.subject | 11(15 -]1)-ABEOTAXANES | pt |
dc.subject | BREVIFOLIOL | pt |
dc.subject | BACCATIN VI | pt |
dc.subject | 10-DEACETYL BACCATIN III | pt |
dc.subject | WINTERSTEIN ESTER | pt |
dc.subject | PHENYLBUTANOIDS | pt |
dc.subject | (-)-RHODODENDROL | pt |
dc.title | PHENYLBUTANOID AND TAXANE-LIKE METABOLITES FROM NEEDLES OF TAXUS-BREVIFOLIA | en |
dc.type | Artigo | |
dcterms.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
dcterms.rightsHolder | Elsevier B.V. | |
unesp.author.lattes | 1308042794786872 | |
unesp.campus | Universidade Estadual Paulista (Unesp), Instituto de Química, Araraquara | pt |
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