Correlation between pain and hyalinization during tooth movement induced by different types of force

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dc.contributor.authorCuoghi, Osmar A. [UNESP]
dc.contributor.authorTopolski, Francielle [UNESP]
dc.contributor.authorFaria, Lorraine P. de [UNESP]
dc.contributor.authorErvolino, Edilson [UNESP]
dc.contributor.authorMicheletti, Kelly R. [UNESP]
dc.contributor.authorMiranda-Zamalloa, Yesselin M. [UNESP]
dc.contributor.authorMoresca, Ricardo
dc.contributor.authorMoro, Alexandre
dc.contributor.authorMendonca, Marcos R. de [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Fed Parana
dc.contributor.institutionUniv Posit
dc.date.accessioned2019-10-04T15:58:25Z
dc.date.available2019-10-04T15:58:25Z
dc.date.issued2019-09-01
dc.description.abstractObjectives: To evaluate the correlation between pain and tissue reactions during induced tooth movement (ITM). Materials and Methods: Forty-two male Wistar rats (Rattus norvegicus; similar to 90 days of age, 300 g) were used. The animals were divided into seven groups of six rats each: one control group and six experimental groups subjected to ITM by continuous force (CF) or interrupted continuous force (ICF) for 1, 3, and 5 days. Hyalinization of the periodontal ligament (PL) and occurrence of pain were observed. Animal behavior (walking, climbing, immobile posture, resting/sleeping, and directed face grooming) and the presence of chemical mediators associated with nociception, cyclooxygenase-2 (COX-2), and interleukin-1 beta (IL-1 beta) in the PL were analyzed. Results: There was a moderate positive correlation between hyalinization and the presence of COX-2 (r(s) = 0.404; P < .05) and IL-1 beta (r(s) = 0.429; P < .05). There was a moderate negative correlation between hyalinization and exploratory behaviors (walking, r = -0.586, P < .01; climbing, r = -0.573, P < .01), and a moderate positive correlation between hyalinization and resting/sleeping (r = 0.467; P < .01). Conclusions: The results suggest a correlation between pain and undesirable tissue reactions in ITM.en
dc.description.affiliationSao Paulo State Univ, Dent Sch Aracatuba, Aracatuba, SP, Brazil
dc.description.affiliationUniv Fed Parana, Curitiba, Parana, Brazil
dc.description.affiliationUniv Posit, Sch Hlth & Biol Sci, Curitiba, Parana, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Dent Sch Aracatuba, Aracatuba, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent788-796
dc.identifierhttp://dx.doi.org/10.2319/041118-273.1
dc.identifier.citationAngle Orthodontist. Newton N: E H Angle Education Research Foundation, Inc, v. 89, n. 5, p. 788-796, 2019.
dc.identifier.doi10.2319/041118-273.1
dc.identifier.issn0003-3219
dc.identifier.lattes4408095517346846
dc.identifier.orcid0000-0003-4859-0583
dc.identifier.urihttp://hdl.handle.net/11449/186285
dc.identifier.wosWOS:000482085000015
dc.language.isoeng
dc.publisherE H Angle Education Research Foundation, Inc
dc.relation.ispartofAngle Orthodontist
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectTooth movement
dc.subjectPain
dc.subjectRats
dc.subjectWistar
dc.subjectBehavior
dc.subjectHyalinization
dc.titleCorrelation between pain and hyalinization during tooth movement induced by different types of forceen
dc.typeArtigo
dcterms.rightsHolderE H Angle Education Research Foundation, Inc
unesp.author.lattes4408095517346846[4]
unesp.author.orcid0000-0003-4859-0583[4]

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