Using natural deep eutectic solvents for the extraction of metabolites in Byrsonima intermedia leaves

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dc.contributor.authorFraige, Karina [UNESP]
dc.contributor.authorArrua, R. Dario
dc.contributor.authorSutton, Adam T.
dc.contributor.authorFunari, Cristiano Soleo [UNESP]
dc.contributor.authorCavalheiro, Alberto José [UNESP]
dc.contributor.authorHilder, Emily F.
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversity of South Australia (UniSA)
dc.date.accessioned2019-10-06T16:57:16Z
dc.date.available2019-10-06T16:57:16Z
dc.date.issued2019-01-01
dc.description.abstractNatural deep eutectic solvents have been used as an alternative to organic solvents for the extraction of plants metabolites, allowing for the extraction of compounds of different polarities, while being inexpensive, non-toxic, and easy to prepare. This work presents the comparison of the chromatographic profiles by high-performance liquid chromatography with diode-array detection obtained from Byrsonima intermedia (Malpighiaceae) using five choline chloride-based natural deep eutectic solvents, in addition to the most used traditional extraction solvents, methanol/water 7:3 and ethanol/water 7:3 v/v. A reference extract was used to tentatively identify compounds by high-performance liquid chromatography with tandem mass spectrometry. The water content appeared to be important for the extraction efficiency and the mixture choline chloride/glycerol was shown to be the best candidate for efficiently extracting this matrix when compared with the traditional extraction media in addition to being far greener as shown by the environmental analysis tool. Seven phenolic compounds (digalloyl quinic acid, proanthocyanidin dimer, galloylproanthocyanidin dimer, quercetin-O-hexoside, galloyl quercetin hexoside, quercetin-O-pentoside, and galloyl quercetin pentoside) were tentatively identified in all extracts. Moreover, the influence of these solvents on the antioxidant activity of the extracts was studied and the results for choline chloride/glycerol extracts were very similar to that of the traditional extraction solvents.en
dc.description.affiliationUNESP-São Paulo State University Institute of Chemistry
dc.description.affiliationFuture Industries Institute University of South Australia (UniSA)
dc.description.affiliationUNESP-São Paulo State University Faculty of Agricultural Sciences
dc.description.affiliationUnespUNESP-São Paulo State University Institute of Chemistry
dc.description.affiliationUnespUNESP-São Paulo State University Faculty of Agricultural Sciences
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2013/07600-3
dc.description.sponsorshipIdFAPESP: 2013/15086-8
dc.description.sponsorshipIdFAPESP: 2016/50009-2
dc.format.extent591-597
dc.identifierhttp://dx.doi.org/10.1002/jssc.201800905
dc.identifier.citationJournal of Separation Science, v. 42, n. 2, p. 591-597, 2019.
dc.identifier.doi10.1002/jssc.201800905
dc.identifier.issn1615-9314
dc.identifier.issn1615-9306
dc.identifier.scopus2-s2.0-85057783499
dc.identifier.urihttp://hdl.handle.net/11449/189942
dc.language.isoeng
dc.relation.ispartofJournal of Separation Science
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectantioxidant activity
dc.subjectByrsonima intermedia
dc.subjectgreen solvents
dc.subjectplant metabolites
dc.titleUsing natural deep eutectic solvents for the extraction of metabolites in Byrsonima intermedia leavesen
dc.typeArtigo
unesp.author.orcid0000-0002-8298-6568[1]

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