Controlled drug delivery vehicles in veterinary oncology: State-of-the-art and future directions

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dc.contributor.authorde Faria Lainetti, Patricia [UNESP]
dc.contributor.authorZuliani, Fernanda [UNESP]
dc.contributor.authorLeis-Filho, Antonio Fernando [UNESP]
dc.contributor.authorFonseca Alves, Ricardo Henrique
dc.contributor.authorFonseca-Alves, Carlos Eduardo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionHarvard University
dc.contributor.institutionUniversidade Paulista-UNIP
dc.date.accessioned2020-12-12T02:08:33Z
dc.date.available2020-12-12T02:08:33Z
dc.date.issued2020-05-01
dc.description.abstractControlled drug delivery systems can be used to carry several anticancer agents, including classical chemotherapeutic agents such as doxorubicin, paclitaxel or cisplatin, and are also used for the encapsulation of tyrosine kinase inhibitors and monoclonal antibodies. Usually, the controlled systems are used to decrease drug toxicity, increase local drug concentration or target specific organs or systems. In dogs, liposomal doxorubicin is the most known controlled drug delivery vehicle in veterinary medicine. However, several antitumor drugs can be encapsulated within these systems. Since the delivery vehicles are a relatively new topic in veterinary oncology, this review aims to discuss the current knowledge regarding the controlled drug delivery vehicles and discuss the current challenges and future direction of its use in veterinary oncology.en
dc.description.affiliationDepartment of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University-UNESP
dc.description.affiliationJohn A. Paulson School of Engineering and Applied Sciences Harvard University
dc.description.affiliationInstitute of Health Sciences Universidade Paulista-UNIP
dc.description.affiliationUnespDepartment of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University-UNESP
dc.identifierhttp://dx.doi.org/10.3390/PR8050541
dc.identifier.citationProcesses, v. 8, n. 5, 2020.
dc.identifier.doi10.3390/PR8050541
dc.identifier.issn2227-9717
dc.identifier.scopus2-s2.0-85085360547
dc.identifier.urihttp://hdl.handle.net/11449/200513
dc.language.isoeng
dc.relation.ispartofProcesses
dc.sourceScopus
dc.subjectDogs
dc.subjectDoxorubicin
dc.subjectNanoparticles
dc.subjectNanotechnology
dc.titleControlled drug delivery vehicles in veterinary oncology: State-of-the-art and future directionsen
dc.typeResenha
unesp.author.orcid0000-0001-8272-7606[1]
unesp.author.orcid0000-0002-1115-8140[4]
unesp.author.orcid0000-0002-6702-6139[5]

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Artigos - Reprodução Animal e Radiologia Veterinária - FMVZ