Influence of clinical therapy and nutritional counseling on the recurrence of urolithiasis

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dc.contributor.authorDamasio, Patrícia Capuzzo
dc.contributor.authorAmaro, Carmen Regina
dc.contributor.authorPadovani, Carlos Roberto [UNESP]
dc.contributor.authorLeitão, Victor Augusto
dc.contributor.authorYamamoto, Hamilto Akihissa [UNESP]
dc.contributor.authorAmaro, João Luiz [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-10-01T13:08:41Z
dc.date.available2014-10-01T13:08:41Z
dc.date.issued2014-06-01
dc.description.abstractPURPOSE: To evaluate the influence of combined clinical therapy and nutritional guidance on the recurrence of urolithiasis. METHODS: From our registry of patients with recurrent urolithiasis we selected 57 who had at least 5-years of follow-up. We collected 24h urine samples in order to analyze Ca, Na, uric acid, citrate, oxalate, and Mg concentrations and to assess urine volume. Patients filled out a clinical questionnaire before treatment, and abdominal radiographs and/or ultrasound were performed both before treatment and during the follow-up period. During follow-up, specific and individualized dietary advice was given based on the individual's metabolic disorders. Patients also received specific pharmacological treatment for their metabolic alterations. Outcome measures were metabolites in urine and the urolith recurrence rate. Pre- and post- intervention values were compared using tests as appropriate. RESULTS: Fifty six of the patients were male and the majority of patients were overweight. The mean BMI was 27 kg/m2. Urinary excretion of calcium, uric acid and sodium decreased significantly over the five year follow-up period. The number of uroliths that formed during the 5-year follow-up also decreased significantly compared to pre-treatment values. CONCLUSION: Individualized dietary advice combined with pharmacological treatment significantly reduces long-term urolithiasis recurrence.en
dc.description.affiliationSao Paulo State University Medical School of Botucatu
dc.description.affiliationUNESP Medical School of Botucatu
dc.description.affiliationUNESP Medical School of Botucatu Department of Biostatistics
dc.description.affiliationUNESP Medical School of Botucatu Department of Urology
dc.description.affiliationUnespSao Paulo State University Medical School of Botucatu
dc.description.affiliationUnespUNESP Medical School of Botucatu
dc.description.affiliationUnespUNESP Medical School of Botucatu Department of Biostatistics
dc.description.affiliationUnespUNESP Medical School of Botucatu Department of Urology
dc.format.extent400-404
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502014000600009
dc.identifier.citationActa Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 29, n. 6, p. 400-404, 2014.
dc.identifier.doi10.1590/S0102-86502014000600009
dc.identifier.fileS0102-86502014000600400.pdf
dc.identifier.issn0102-8650
dc.identifier.lattes8727897080522289
dc.identifier.scieloS0102-86502014000600400
dc.identifier.urihttp://hdl.handle.net/11449/109932
dc.identifier.wosWOS:000338015900009
dc.language.isoeng
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.relation.ispartofActa Cirúrgica Brasileira
dc.relation.ispartofjcr0.933
dc.relation.ispartofsjr0,395
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectUrolithiasisen
dc.subjectDrug Therapyen
dc.subjectFeeding Behavioren
dc.subjectRecurrenceen
dc.titleInfluence of clinical therapy and nutritional counseling on the recurrence of urolithiasisen
dc.typeArtigo
unesp.author.lattes8727897080522289[3]
unesp.author.orcid0000-0002-7719-9682[3]
unesp.author.orcid0000-0003-3745-0761[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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Artigos - Bioestatística - IBB
Artigos - Urologia - FMB