Effect of Usnic Acid on Candida orthopsilosis and C. parapsilosis

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dc.contributor.authorPires, Regina Helena [UNESP]
dc.contributor.authorLucarini, Rodrigo
dc.contributor.authorMendes-Giannini, Maria José Soares [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Franca
dc.date.accessioned2014-05-20T13:23:50Z
dc.date.available2014-05-20T13:23:50Z
dc.date.issued2012-01-01
dc.description.abstractThe activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentration. The in vitro studies support further efforts to determine whether usnic acid can be used clinically to cure patients with Candida infections.en
dc.description.affiliationUniv Estadual Paulista, UNESP, Araraquara, SP, Brazil
dc.description.affiliationUniv Franca, Franca, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Araraquara, SP, Brazil
dc.format.extent595-597
dc.identifierhttp://dx.doi.org/10.1128/AAC.05348-11
dc.identifier.citationAntimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 56, n. 1, p. 595-597, 2012.
dc.identifier.doi10.1128/AAC.05348-11
dc.identifier.fileWOS000298404900080.pdf
dc.identifier.issn0066-4804
dc.identifier.orcid0000-0002-8059-0826
dc.identifier.urihttp://hdl.handle.net/11449/7256
dc.identifier.wosWOS:000298404900080
dc.language.isoeng
dc.publisherAmer Soc Microbiology
dc.relation.ispartofAntimicrobial Agents and Chemotherapy
dc.relation.ispartofjcr4.255
dc.relation.ispartofsjr2,291
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleEffect of Usnic Acid on Candida orthopsilosis and C. parapsilosisen
dc.typeArtigo
dcterms.licensehttp://journals.asm.org/site/misc/ASM_Author_Statement.xhtml
dcterms.rightsHolderAmer Soc Microbiology
unesp.author.orcid0000-0002-6004-5951[1]
unesp.author.orcid0000-0002-8059-0826[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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