Non-Thermal Atmospheric Pressure Plasma Application in Endodontics

dc.contributor.authorMuniz, Ana Bessa [UNESP]
dc.contributor.authorVegian, Mariana Raquel da Cruz [UNESP]
dc.contributor.authorPereira Leite, Lady Daiane [UNESP]
dc.contributor.authorda Silva, Diego Morais [UNESP]
dc.contributor.authorMoreira Milhan, Noala Vicensoto [UNESP]
dc.contributor.authorKostov, Konstantin Georgiev [UNESP]
dc.contributor.authorKoga-Ito, Cristiane Yumi [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2023-07-29T13:57:25Z
dc.date.available2023-07-29T13:57:25Z
dc.date.issued2023-05-01
dc.description.abstractThe failure of endodontic treatment is frequently associated with the presence of remaining microorganisms, mainly due to the difficulty of eliminating the biofilm and the limitation of conventional irrigation solutions. Non-thermal atmospheric pressure plasma (NTPP) has been suggested for many applications in the medical field and can be applied directly to biological surfaces or indirectly through activated liquids. This literature review aims to evaluate the potential of NTPP application in Endodontics. A search in the databases Lilacs, Pubmed, and Ebsco was performed. Seventeen manuscripts published between 2007 and 2022 that followed our established inclusion criteria were found. The selected manuscripts evaluated the use of NTPP regarding its antimicrobial activity, in the direct exposure and indirect method, i.e., plasma-activated liquid. Of these, 15 used direct exposure. Different parameters, such as working gas and distance from the apparatus to the substrate, were evaluated in vitro and ex vivo. NTPP showed a disinfection property against important endodontic microorganisms, mainly Enterococcus faecalis and Candida albicans. The antimicrobial potential was dependent on plasma exposure time, with the highest antimicrobial effects over eight minutes of exposure. Interestingly, the association of NTPP and conventional antimicrobial solutions, in general, was shown to be more effective than both treatments separately. This association showed antimicrobial results with a short plasma exposure time, what could be interesting in clinical practice. However, considering the lack of standardization of the direct exposure parameters and few studies about plasma-activated liquids, more studies in the area for endodontic purposes are still required.en
dc.description.affiliationDepartment of Environment Engineering and Sciences Applied to Oral Health Graduate Program São José dos Campos Institute of Science and Technology São Paulo State University (UNESP), SP
dc.description.affiliationDepartment of Physics Faculty of Engineering in Guaratinguetá São Paulo State University (UNESP), SP
dc.description.affiliationUnespDepartment of Environment Engineering and Sciences Applied to Oral Health Graduate Program São José dos Campos Institute of Science and Technology São Paulo State University (UNESP), SP
dc.description.affiliationUnespDepartment of Physics Faculty of Engineering in Guaratinguetá São Paulo State University (UNESP), SP
dc.identifierhttp://dx.doi.org/10.3390/biomedicines11051401
dc.identifier.citationBiomedicines, v. 11, n. 5, 2023.
dc.identifier.doi10.3390/biomedicines11051401
dc.identifier.issn2227-9059
dc.identifier.scopus2-s2.0-85160772135
dc.identifier.urihttp://hdl.handle.net/11449/248923
dc.language.isoeng
dc.relation.ispartofBiomedicines
dc.sourceScopus
dc.subjectendodontics
dc.subjectmicroorganism
dc.subjectnon-thermal plasma
dc.subjectroot canal
dc.titleNon-Thermal Atmospheric Pressure Plasma Application in Endodonticsen
dc.typeResenha
unesp.author.orcid0000-0003-0271-9142[4]
unesp.author.orcid0000-0002-9137-8476[5]
unesp.author.orcid0000-0002-9821-8088[6]
unesp.author.orcid0000-0002-2416-2173[7]
unesp.departmentFísica e Química - FEGpt

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