Total protein level reduction of odontopathogens biofilms by rosmarinus officinalis L. (rosemary) extract: An analysis on candida albicans and streptococcus mutans

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dc.contributor.authorde Oliveira, Jonatas Rafael [UNESP]
dc.contributor.authorSantana-Melo, Gabriela de Fátima [UNESP]
dc.contributor.authorCamargo, Samira Esteves Afonso
dc.contributor.authorde Vasconcellos, Luana Marotta Reis [UNESP]
dc.contributor.authorde Oliveira, Luciane Dias [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCollege of Dentistry
dc.date.accessioned2019-10-06T16:34:49Z
dc.date.available2019-10-06T16:34:49Z
dc.date.issued2019-01-01
dc.description.abstractObjective: The resistance of fungi and bacteria to the available antimicrobials has increased and the development of alternative products to control them has become a very requirement. The use of plant products could be a viable option due to the efficacy, viability, and availability they present. Thereby, this study evaluated the effect of R. officinalis L. extract on C. albicans and S. mutans biofilms, by the total protein level analysis presented by the microorganisms. Material and Methods: For this purpose, monomicrobial biofilms were formed for 48 h and exposed to the R. officinalis L. extract for 5 min. Then, total protein quantification was performed by Lowry method. Results: The analysis showed significant total protein reduction of the biofilms after exposure to the plant extract, with 39 ± 11%, for C. albicans, and 32 ± 11%, for S. mutans. Conclusion: R. officinalis L. extract decreased the total protein level in both biofilms. Thus, C. albicans and S. mutans protein composition could be a target for action of antimicrobial agents.en
dc.description.affiliationSão Paulo State University (Unesp) Institute of Science and Technology São José dos Campos-Department of Biosciences and Oral Diagnosis
dc.description.affiliationUniversity of Florida College of Dentistry Department of Restorative Dental Sciences
dc.description.affiliationUnespSão Paulo State University (Unesp) Institute of Science and Technology São José dos Campos-Department of Biosciences and Oral Diagnosis
dc.format.extent260-266
dc.identifierhttp://dx.doi.org/10.14295/bds.2019.v22i2.1679
dc.identifier.citationBrazilian Dental Science, v. 22, n. 2, p. 260-266, 2019.
dc.identifier.doi10.14295/bds.2019.v22i2.1679
dc.identifier.issn2178-6011
dc.identifier.scopus2-s2.0-85067296720
dc.identifier.urihttp://hdl.handle.net/11449/189251
dc.language.isoeng
dc.relation.ispartofBrazilian Dental Science
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBiofilms
dc.subjectCandida albicans
dc.subjectProteins
dc.subjectRosmarinus officinalis
dc.subjectStreptococcus mutans
dc.titleTotal protein level reduction of odontopathogens biofilms by rosmarinus officinalis L. (rosemary) extract: An analysis on candida albicans and streptococcus mutansen
dc.titleRedução do nível de proteína total de biofilmes de odontopatógenos por extrato de rosmarinus officinalis L. (alecrim): uma análise sobre candida albicans e streptococcus mutanspt
dc.typeArtigo

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