Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

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2-s2.0-85041593745.pdf (2.84 MB)

2-s2.0-85041593745.pdf

External sources

http://dx.doi.org/10.1016/j.dib.2018.01.007

External sources

http://dx.doi.org/10.1016/j.dib.2018.01.007

Date

Authors

Bragato, Jaqueline Poleto

Melo, Larissa Martins

Venturin, Gabriela Lovizutto

Rebech, Gabriela Torres

Garcia, Leandro Encarnação

Lopes, Flavia Lombardi

de Lima, Valéria Marçal Felix

Publisher

Elsevier

Type

Article

Access right

Acesso aberto

Files

2-s2.0-85041593745.pdf (2.84 MB)

2-s2.0-85041593745.pdf

External sources

http://dx.doi.org/10.1016/j.dib.2018.01.007

External sources

http://dx.doi.org/10.1016/j.dib.2018.01.007

Abstract

This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program.

Keywords

Dog , Leishmania infantum , miRNA

Language

English

Citation

Data in Brief, v. 17, p. 218-225.

URI

http://hdl.handle.net/11449/170630

Sponsors

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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