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Study of some volatile compounds evolved from the thermal decomposition of atenolol

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Springer

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Abstract

Simultaneous thermogravimetry-differential scanning calorimetry (TG-DSC) and coupled thermogravimetry-infrared spectroscopy (TG-FTIR) analyses were used to study the antihypertensive drug atenolol. The TG-DSC curves provided information concerning the thermal stability and decomposition profiles of the compound. From the TG-FTIR coupled techniques, it was possible to identify ammonia and isopropylamine as possible volatile compounds released during the thermal decomposition of the drug.

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Keywords

Atenolol, Thermal behavior, Coupled thermogravimetry-infrared spectroscopy

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English

Citation

Journal Of Thermal Analysis And Calorimetry. Dordrecht: Springer, v. 115, n. 3, p. 2517-2520, 2014.

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Faculdade de Ciências
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Campus: Bauru


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