Publicação:
Efeitos do extrato aquoso de cebola (Allium cepa L.) sobre a função renal e a pressão arterial em ratos Wistar

dc.contributor.authorCampos, K. E. [UNESP]
dc.contributor.authorBalbi, A. P C
dc.contributor.authorAlves, M. J Q F [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:21:38Z
dc.date.available2014-05-27T11:21:38Z
dc.date.issued2005-10-01
dc.description.abstractThe vegetal species, Allium cepa, known as onion, is widely used in the folk medicine as diuretic, besides it has been used on the bronchitis, cough, cardiovascular diseases and hypertension treatment. In this study we evaluate the onion aqueous extract (AE) effect on water flow and electrolytes in anesthetized Wistar rats, besides we also evaluate arterial pressure alterations. Two groups were studied: Group 1 (control) - oral tratment with 1.0 mL of distilled water, and Group 2 (experimental) - oral treatment with 1.0 mL of AE 20%. The rats were anesthetized and we canulate the trachea, left carotide artery (for arterial pressure measurement and blood collecting), jugular vein (to execute inulin perfusion - to register glomerular filtration), and urinary bladder (to collect urine). The Group 1 results had shown that the animals had not presented significant alterations (p>0.05) in the analyzed parameters. The animals of Group 2 had a significant reduction (p<0.05) in the arterial pressure (22.0%). However, there were not significant alterations in renal parameters (p>0.05). These results show that the treatment with the AE lead a hypotensor effect in anesthetized Wistar rats, but not followed by renal parameters alterations.en
dc.description.affiliationDepartamento de Fisiologia Instituto de Biociências UNESP/Campus de Botucatu-SP, Cx. P. 510, CEP 18618-000, Botucatu-SP
dc.description.affiliationDepartamento de Fisiologia Faculdade de Medicina de Ribeirão Preto USP/Campus de Ribeirão Preto-SP
dc.description.affiliationUnespDepartamento de Fisiologia Instituto de Biociências UNESP/Campus de Botucatu-SP, Cx. P. 510, CEP 18618-000, Botucatu-SP
dc.format.extent24-29
dc.identifierhttp://www.ibb.unesp.br/Home/Departamentos/Botanica/RBPM-RevistaBrasileiradePlantasMedicinais/artigo6_v8_n1.pdf
dc.identifier.citationRevista Brasileira de Plantas Medicinais, v. 8, n. 1, p. 24-29, 2005.
dc.identifier.file2-s2.0-32144447430.pdf
dc.identifier.issn1516-0572
dc.identifier.scopus2-s2.0-32144447430
dc.identifier.urihttp://hdl.handle.net/11449/68443
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Plantas Medicinais
dc.relation.ispartofsjr0,199
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectArterial hypertension
dc.subjectOnion
dc.subjectRats wistar
dc.subjectRenal function
dc.subjectelectrolyte
dc.subjectinulin
dc.subjectonion extract
dc.subjectanesthesia
dc.subjectanimal experiment
dc.subjectarterial pressure
dc.subjectbronchitis
dc.subjectcannulation
dc.subjectcardiovascular disease
dc.subjectcarotid artery
dc.subjectcontrolled study
dc.subjectcoughing
dc.subjectdiuresis
dc.subjectdrug effect
dc.subjectelectrolyte balance
dc.subjectglomerulus filtration
dc.subjecthypertension
dc.subjecthypotension
dc.subjectjugular vein
dc.subjectkidney function
dc.subjectnonhuman
dc.subjectrat
dc.subjecttrachea
dc.subjecttraditional medicine
dc.subjecturine volume
dc.subjectwater flow
dc.subjectAllium cepa
dc.subjectAnimalia
dc.subjectRattus norvegicus
dc.titleEfeitos do extrato aquoso de cebola (Allium cepa L.) sobre a função renal e a pressão arterial em ratos Wistarpt
dc.title.alternativeEffects of onion aqueous extract under the renal function and the arterial pressure in Wistar ratsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbpm/paboutj.htm#03
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentFisiologia - IBBpt

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